Weight-Loss surgery before knee replacement: does it help or hurt?
NCT ID NCT06433700
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study examined nearly 100,000 people who had knee replacement for arthritis to see if those who previously had weight-loss surgery faced different risks of complications or needing another surgery. Researchers focused on how body weight at the time of knee replacement and the type of weight-loss surgery affected outcomes. The goal is to help doctors better predict and improve results for these patients.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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99,965 people
The number who actually took part.
- Started
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Jun 2024
- Finished
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Feb 2025
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
The investigators will include patients with primary/idiopathic or secondary (due to meniscus or cruciate ligament lesion) osteoarthritis (OA) who received primary KA in the period from 2011 and 2 years earlier to data-extraction date. Patients will be identified from the DKR. Patients are followed for 2 years, until first revision, death or migration, whichever comes first.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Primary knee arthroplasty due to osteoarthritis Exclusion Criteria: * Primary knee arthroplasty due to traumatic osteoarthritis.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Orthopaedic department, Bispebjerg Hospital
Copenhagen, Denmark
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Can testosterone shield muscle during rapid weight loss?
- Can Weight-Loss surgery weaken protein digestion in older adults?
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- Can a phone app ease the journey through Weight-Loss surgery?
- Could a joint injection of growth hormone and Platelet-Rich plasma offer a new path for arthritis relief?