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Posterior corneal dystrophy
MONDO:0020214Posterior corneal dystrophies refers to a group of rare genetically determined corneal dystrophies (CDs) characterized by lesions affecting the corneal endothelium and Descemet membrane, and variable effects on vision depending on the type of dystrophy.
40 clinical trials for this condition and its sub-types, 0 tagged with Posterior corneal dystrophy itself.
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Sub-types of Posterior corneal dystrophy
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Fuchs' endothelial dystrophy 33 trials
8 sub-types
- Corneal dystrophy, Fuchs endothelial, 1 1 trial
- Corneal dystrophy, Fuchs endothelial, 3 0 trials
- Corneal dystrophy, Fuchs endothelial, 4 0 trials
- Corneal dystrophy, Fuchs endothelial, 6 0 trials
- Corneal dystrophy, Fuchs endothelial, 8 0 trials
- Corneal dystrophy, fuchs endothelial, 2 0 trials
- Corneal dystrophy, fuchs endothelial, 5 0 trials
- Corneal dystrophy, fuchs endothelial, 7 0 trials
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4 sub-types
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Central cloudy dystrophy of François 0 trials
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Cornea transplant showdown: which surgery gives sharper sight?
Disease control OngoingThis study compares two types of cornea transplant surgery—DSAEK and DMEK—in 220 adults with corneal swelling or Fuchs' dystrophy. The goal is to see which procedure leads to better vision and patient satisfaction one year after surgery. Participants will be randomly assigned to …
Sponsor: University Hospital, Antwerp • Aim: Disease control
Last updated Sep 16, 2026 00:00 UTC
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Eye transplant showdown: which surgery saves sight best?
Disease control OngoingThis study compares two types of corneal transplant surgery (UT-DSAEK and DMEK) in 160 people with Fuchs dystrophy, a condition that clouds the cornea. It also tests whether a drug called rho-kinase inhibitor can reduce loss of important eye cells after surgery. The goal is to fi…
Phase 3 • Sponsor: Stanford University • Aim: Disease control
Last updated Aug 19, 2026 00:00 UTC
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Eye drops may shield the cornea after cataract surgery
Prevention By invitation onlyResearchers are testing whether netarsudil eye drops can protect the cornea in people with Fuchs endothelial corneal dystrophy and glaucoma who have cataract surgery. The study enrolls 50 adults aged 40 to 90. Participants use either netarsudil or a placebo drop daily for four we…
Sponsor: University Hospital Dubrava • Aim: Prevention
Last updated Sep 11, 2026 00:00 UTC
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Contact lens stress test for fuchs dystrophy eyes
Knowledge-focused CancelledThis study aimed to compare how corneas with Fuchs endothelial corneal dystrophy (FECD) and healthy corneas swell and recover after wearing a contact lens for three hours. Researchers planned to measure corneal thickness before and after the lens was removed, tracking swelling an…
Phase 1/2 • Sponsor: Massachusetts Eye and Ear Infirmary • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:09 UTC
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Does donor diabetes impact corneal transplant outcomes?
Knowledge-focused By invitation onlyThis study looks at whether corneas from donors with diabetes work as well as those from donors without diabetes after a specific type of corneal transplant called DMEK. Researchers will track 570 participants for 5 years to measure cell loss and overall transplant success. The g…
Sponsor: Case Western Reserve University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:08 UTC