Cornea transplant showdown: which surgery gives sharper sight?
NCT ID NCT05436665
First seen Dec 18, 2025 · Last updated Jun 22, 2026 · Updated 26 times
Summary
This study compares two types of cornea transplant surgery—DSAEK and DMEK—in 220 adults with corneal swelling or Fuchs' dystrophy. The goal is to see which procedure leads to better vision and patient satisfaction one year after surgery. Participants will be randomly assigned to one of the two surgeries and followed for 12 months.
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This is a summary of
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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AZ Imelda
RECRUITINGBonheiden, Belgium
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Contact Email: •••••@•••••
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AZ Maria Middelares
RECRUITINGGhent, Oost-Vlaanderen, Belgium
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AZ Monica (campus Deurne)
RECRUITINGDeurne, Belgium
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AZ Sint-Jan Brugge
RECRUITINGBruges, West-Vlaanderen, Belgium
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Antwerp University Hospital
RECRUITINGEdegem, Antwerp, 2650, Belgium
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Contact Email: •••••@•••••
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CHU Liège
RECRUITINGLiège, Belgium
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Erasmus ziekenhuis Brussel
RECRUITINGBrussels, Belgium
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UZ Brussel
RECRUITINGBrussels, Belgium
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UZ Gent
RECRUITINGGhent, Belgium
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Contact Email: •••••@•••••
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UZ Leuven
RECRUITINGLeuven, Belgium
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Contact
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Ziekenhuis Oost-Limburg (ZOL)
RECRUITINGGenk, Belgium
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What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Cornea transplant surgery (DSAEK or DMEK procedure)
What this could lead to
If successful, this study could show which cornea transplant method gives better vision and patient satisfaction, helping doctors choose the best option for each patient.
What could go wrong
This is a comparative effectiveness trial, not a test of a new drug or cure. Results may not apply to all patients, and both procedures carry standard surgical risks like infection or graft failure.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.