Peripheral vascular disease

This study looked at how well the AURYON atherectomy device works for people with peripheral artery disease (PAD), where leg arteries become blocked. The device uses a laser to vaporize plaque and restore blood flow. Researchers followed 102 patients to see if the procedure was s…

This study tested two ways to treat blocked leg arteries in 47 people with leg pain when walking. One group had a special device to remove plaque (atherectomy) followed by a drug-coated balloon, while the other had standard balloon angioplasty followed by the same drug-coated bal…

This study tested whether injecting donor stem cells into the leg muscles before amputation could prevent wound problems and reduce the need for more amputations. 81 people scheduled for leg amputation due to poor blood flow took part. The main goal was to check safety, not yet t…

This study tested several simple bedside tests—like ankle and toe blood pressure measurements and handheld Dopplers—to see how well they detect poor leg circulation (peripheral arterial disease) in 604 people with diabetes. The results were compared to advanced imaging scans (CTA…

Researchers are testing whether a home telehealth system can prevent complications after vascular surgery that involves a groin incision. Patients scheduled for these procedures are randomly assigned to receive either standard discharge instructions or a tablet with a weight scal…

This study tested whether using nerve blocks and sedation instead of general anesthesia could make upper leg amputation surgery safer for high-risk patients, such as the elderly or those with diabetes or heart disease. Thirty participants received ultrasound-guided nerve blocks a…

This study tested whether reflexology or classical hand massage can reduce pain, anxiety, and improve vital signs in 70 patients who had coronary angiography. Participants received one of the two massage types, and their pain and anxiety levels were measured. The goal is to see i…

This study is looking at whether peripheral artery disease (PAD) is linked to lower levels of regenerative cells in the blood. Researchers will compare blood samples from adults with PAD to those without the condition, measuring the number of certain progenitor cells and markers …

This study looks at how eating a high-fat meal changes levels of certain fats in the blood called ceramides, and whether those changes affect blood vessel function. Healthy adults aged 18 to 40 will eat either a meal rich in long-chain fatty acids (which raise ceramides) or mediu…

This study watches and records pain levels at four key moments during radiofrequency ablation for varicose veins—from needle insertion to the end of the procedure. Researchers will look at how factors like age, gender, and body mass index relate to pain. The goal is to find patte…

This study tested how different levels of leg compression affect blood circulation in 30 adults after surgery. Participants received three pressure levels (low, moderate, high) on their calves, and blood flow was measured non-invasively. The goal is to gather early evidence for m…

This completed study tested a special guidewire with a sensor that measures electrical properties of tissues in people with peripheral artery disease. The goal was to see if the sensor could tell the difference between various tissues, like the artery wall and surrounding areas. …

This study looked at a molecule called microRNA-210 in 230 people with peripheral artery disease (PAD), a condition where leg arteries become blocked. Researchers measured its levels and linked them to oxidative stress and walking ability. The goal was to understand how this mole…

This study combines data from nearly 1,000 patients who received a special stent-graft (the GORE VIABAHN with a heparin coating) for peripheral artery disease in the leg. Researchers want to see how well the device keeps arteries open over time and which patient factors affect su…

This study looked at whether shining a special light on the head (called transcranial photobiomodulation) can improve blood flow in the brain and boost thinking skills. 24 healthy adults aged 18 to 80 took part. The goal was to gather information, not to treat or cure any disease…

This study looked at whether using telemedicine (video or phone consultations) can help people in rural communities with leg wounds get specialist care more quickly. Researchers compared the time from when a wound was found to when a specialist saw the patient, either through tel…