Palsy
MONDO:0006496A general term most often used to describe severe or complete loss of muscle strength due to motor system disease from the level of the cerebral cortex to the muscle fiber. This term may also occasionally refer to a loss of sensory function. (From Adams et al., Principles of Neurology, 6th ed, p45)
Also known as: Plegia, Plegias
843 clinical trials for this condition and its sub-types, 36 tagged with Palsy itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Palsy
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Cerebral palsy 441 trials · 497 incl. sub-types
5 sub-types
- Spastic cerebral palsy 75 trials · 228 incl. sub-types Sub-types →
- Athetoid cerebral palsy 6 trials
- Ataxic cerebral palsy 4 trials Sub-types →
- Mixed cerebral palsy 1 trial Sub-types →
- Hypotonic cerebral palsy 0 trials
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Hemiplegia 175 trials · 178 incl. sub-types
1 sub-type
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Quadriplegia 73 trials
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Paraplegia 47 trials · 68 incl. sub-types
2 sub-types
- Hereditary spastic paraplegia 27 trials · 33 incl. sub-types Sub-types →
- Brown-Sequard syndrome 0 trials
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Facial paralysis 19 trials · 34 incl. sub-types
2 sub-types
- Bell's palsy 29 trials Sub-types →
- Exophthalmic ophthalmoplegia 0 trials
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Respiratory paralysis 20 trials
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Erb palsy 11 trials
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Ophthalmoplegia 0 trials · 11 incl. sub-types
3 sub-types
- Progressive external ophthalmoplegia 4 trials · 8 incl. sub-types Sub-types →
- Internuclear ophthalmoplegia 3 trials
- Exophthalmic ophthalmoplegia 0 trials
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Progressive bulbar palsy 5 trials
1 sub-type
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Klumpke's paralysis 0 trials
Most studied deeper sub-types
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Can a brain implant let paralyzed people control computers with their minds?
Disease control OngoingThis study tests a device called a motor neuroprosthesis, an implantable brain computer interface designed to help people with severe paralysis control digital devices like computers or tablets. The device aims to bypass damaged motor pathways and transmit brain signals directly …
Sponsor: Synchron Medical, Inc. • Aim: Disease control
Last updated Sep 10, 2026 00:00 UTC
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Could a simple drug cut dangerous blood pressure swings in liver transplants?
Disease control OngoingThis study tests whether a drug called Angiotensin II can help control blood pressure during liver transplant surgery, reducing the need for other strong blood pressure medicines. It involves 50 adults with severe liver disease who are receiving a liver from a deceased donor. The…
Phase 2/3 • Sponsor: University of California, San Francisco • Aim: Disease control
Last updated Jun 27, 2026 11:03 UTC
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Spinal shock: new combo may get paralyzed patients stepping overground
Disease control OngoingThis early-phase study tests whether combining noninvasive spinal cord stimulation with the drug buspirone can help people with severe spinal cord injury take steps overground. Fifteen participants who have been paralyzed for at least a year will undergo various training and meas…
Early phase 1 • Sponsor: University of Louisville • Aim: Disease control
Last updated Jun 27, 2026 11:01 UTC
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Could your own fat help you walk again? new stem cell trial for paralysis
Disease control OngoingThis study tests if stem cells taken from a patient's own belly fat and injected into the spine can safely help restore movement and feeling after a spinal cord injury. About 40 adults with paralysis will receive the treatment. The goal is to see if this approach can improve func…
Phase 2 • Sponsor: Mayo Clinic • Aim: Disease control
Last updated Jun 27, 2026 07:54 UTC
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Desperate family gets one chance at stem cell therapy for cerebral palsy
Disease control Expanded access (ended)This study gave stem cell infusions to one person with severe cerebral palsy who had no other treatment options. The goal was to improve their quality of life, not to cure the condition. The person received 8 infusions of their own stem cells, taken from fat tissue.
Sponsor: Hope Biosciences Research Foundation • Aim: Disease control
Last updated Jun 27, 2026 07:52 UTC
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Own stem cells infused in spinal cord injury hope
Disease control Expanded access (ended)This expanded access program gives one patient with a spinal cord injury at the C5-C7 level a single infusion of their own stem cells (HB-adMSCs). The stem cells are taken from the patient's fat tissue and grown in a lab before being given back. The goal is to see if this approac…
Sponsor: Hope Biosciences LLC • Aim: Disease control
Last updated Jun 27, 2026 07:52 UTC
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Hidden blood vessel damage may predict heart surgery complications
Knowledge-focused CancelledThis study investigates whether patients with pre-existing endothelial dysfunction (damage to the inner lining of blood vessels) are more likely to develop vasoplegia (a dangerous drop in blood pressure) after cardiac surgery using a heart-lung machine. Researchers will measure v…
Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC