Osteoarthritis, hand
MONDO:0006632Osteoarthritis of the hands usually happens as part of nodal osteoarthritis (a form of osteoarthritis that runs in families). This mainly affects women and often starts in your 40s or 50s, around the menopause (the time when menstruation ends and it’s no longer possible to have children).
105 clinical trials for this condition and its sub-types, 69 tagged with Osteoarthritis, hand itself.
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Can a common arthritis drug stop hand joint damage?
Disease control Not yet recruitingThis study tests whether methotrexate, a drug used for other types of arthritis, can slow joint damage in people with painful hand osteoarthritis that hasn't gotten better with standard treatments. About 170 adults with erosive hand osteoarthritis will receive either methotrexate…
Phase 2/3 • Sponsor: Centre Hospitalier Universitaire de Nice • Aim: Disease control
Last updated Jun 27, 2026 12:02 UTC
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Could a Baby's cord membrane ease thumb arthritis pain?
Disease control Not yet recruitingThis study tests whether a piece of human umbilical cord membrane can be used as a cushion in the thumb joint to treat arthritis. About 22 people with thumb arthritis who haven't improved with standard care will receive the implant during surgery. Researchers will track pain, thu…
Phase 2 • Sponsor: TBF Genie Tissulaire • Aim: Disease control
Last updated Jun 27, 2026 09:09 UTC
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New scan aims to tell two types of hand arthritis apart
Diagnosis Not yet recruitingThis study tests a special imaging agent (99mTc-NTP 15-5) to see if it can spot arthritis-damaged joints in the hands and tell the difference between osteoarthritis and rheumatoid arthritis. About 80 adults with one of these conditions will get a scan. The goal is to improve diag…
Phase 2 • Sponsor: Centre Jean Perrin • Aim: Diagnosis
Last updated Jul 12, 2026 00:00 UTC
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Thumb arthritis surgery showdown: which operation offers faster relief?
Symptom relief Not yet recruitingThis study compares two surgical treatments for thumb arthritis: a prosthetic joint replacement (arthroplasty) versus removal of a small bone at the thumb base (trapeziectomy). Researchers will enroll 64 adults aged 18-69 with thumb arthritis that hasn't improved with non-surgica…
Sponsor: Sahlgrenska University Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 12:28 UTC
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Thumb arthritis relief? new trial tests PRP shots
Symptom relief Not yet recruitingThis study tests whether a single injection of platelet-rich plasma (PRP) can reduce pain and improve hand function in adults with thumb base osteoarthritis. 88 participants will receive either PRP or a placebo (saline) injection and be followed for one year. The goal is to see i…
Phase 2 • Sponsor: Goed Medisch Centrum • Aim: Symptom relief
Last updated Jun 27, 2026 12:05 UTC
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Scientists watch thumb muscles in action to improve osteoarthritis rehab
Knowledge-focused Not yet recruitingThis study looks at how two thumb muscles work in people with and without thumb base osteoarthritis while they do six daily tasks like turning a key or writing. Researchers will use sticky sensors to record muscle activity. The goal is to find differences that could lead to bette…
Sponsor: University of Malaga • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:02 UTC
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3D models reveal best thumb surgery for arthritis pain
Knowledge-focused Not yet recruitingThis study looks at how thumb arthritis changes joint pressure and how two types of surgery (with or without a metal implant) affect that pressure. Researchers will use CT scans and computer models to simulate loads in the thumb joint. 40 adults aged 50 to 88 with moderate to sev…
Sponsor: Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:00 UTC
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Thumb arthritis study aims to pinpoint best exercises for hand strength
Knowledge-focused Not yet recruitingThis study looks at how two thumb muscles work during different exercises in people with and without thumb base osteoarthritis. Researchers will measure muscle activity using sensors while participants perform everyday tasks like turning a key or picking up a coin. The goal is to…
Sponsor: University of Malaga • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:06 UTC