Orthostatic hypotension

This study tests whether combining two drugs, droxidopa and pyridostigmine, can improve a sudden drop in blood pressure when standing up (orthostatic hypotension) without making high blood pressure worse when lying down. The trial enrolls people with neurogenic orthostatic hypote…

This study tests whether transcutaneous spinal cord stimulation (TSCS) — a gentle electrical current applied through the skin — can help veterans with chronic spinal cord injury (SCI) better regulate blood pressure during exercise and cold exposure. Participants will receive both…

This study tests whether taking extra salt (5 grams per day in capsules) can improve symptoms and quality of life in older adults (65+) who experience dizziness and falls due to orthostatic hypotension. The trial involves 42 participants and lasts 12 months, focusing on whether s…

This study looks at how the body's automatic nervous system controls blood flow in abdominal veins and how that might lead to high blood pressure in people with Multiple System Atrophy (MSA). Researchers will measure vein responses in about 16 participants aged 40-80 who have MSA…

This study looks at whether drinking 16 ounces of water raises blood pressure more in the morning or the afternoon in people with orthostatic hypotension (a condition where blood pressure drops when standing). Twenty participants will drink water at two different times of day, an…

This study looks at whether drinking water raises blood pressure as much the second time if you've already had a full glass a few hours earlier. Researchers are testing 20 adults with orthostatic hypotension, a condition where blood pressure drops when standing. Participants will…