Water pressure: can a second glass still boost blood pressure?
NCT ID NCT00580996
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looks at whether drinking water raises blood pressure as much the second time if you've already had a full glass a few hours earlier. Researchers are testing 20 adults with orthostatic hypotension, a condition where blood pressure drops when standing. Participants will drink either 16 ounces or 1 ounce of water, and their blood pressure and heart rate will be measured.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- water
- What this could lead to
- If it works, this could help doctors understand how to best use water to manage blood pressure drops in orthostatic hypotension.
- What could go wrong
- This is a very small, early-stage study with only 20 participants. It is not testing a new treatment, just a physiological effect, so it may not change clinical practice.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
-
About 20 people
The number the study aims to enrol. It can still change while the study runs.
- Start date
-
Jul 2006
- Expected to finish
-
Dec 2029
An estimate. End dates often move.
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
18 to 80 years
- Sex
-
Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * orthostatic hypotension (fall in BP\>20/10 mmHg) * pressor response to water in other studies * Age 18-80 years Exclusion Criteria: * pregnancy
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Vanderbilt University
Nashville, Tennessee, 37232, United States
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Other studies related to the condition(s) this trial covers.
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