Orofacial cleft
MONDO:0000358A disorder of facial skeleton that is characterized by cleft lip and/or cleft palate that result in feeding, speech and hearing problems caused by failures during development.
70 clinical trials for this condition and its sub-types, 4 tagged with Orofacial cleft itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Orofacial cleft
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Cleft palate 34 trials · 35 incl. sub-types
9 sub-types
- Isolated cleft palate 3 trials Sub-types →
- Submucosal cleft palate 1 trial
- Kuster syndrome 0 trials
- Rapp-Hodgkin syndrome 0 trials
- Bifid uvula 0 trials
- Cleft hard palate 0 trials
- Cleft palate with or without ankyloglossia, X-linked 0 trials
- Cleft soft palate 0 trials
- Soft and hard cleft palate 0 trials
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Cleft lip 31 trials
3 sub-types
- Kuster syndrome 0 trials
- Rapp-Hodgkin syndrome 0 trials
- Isolated cleft lip 0 trials Sub-types →
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Cleft lip/palate 31 trials
4 sub-types
- Orofacial cleft 10 0 trials
- Orofacial cleft 11 0 trials
- Orofacial cleft 15 0 trials
- Orofacial cleft 5 0 trials
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Cleft lip and alveolus 17 trials
1 sub-type
- Orofacial cleft 5 0 trials
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Orofacial cleft 1 1 trial
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GRHL3-related orofacial clefting 0 trials
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Orofacial cleft 12 0 trials
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Orofacial cleft 13 0 trials
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Orofacial cleft 2 0 trials
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Orofacial cleft 4 0 trials
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Orofacial cleft 7 0 trials
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Orofacial cleft 8 0 trials
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Orofacial cleft 9 0 trials
Most studied deeper sub-types
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Storytime before surgery: could a toy ease Kids' fears?
Symptom relief Stopped earlyThis pilot study looked at whether an interactive storyteller called LUNII could lower anxiety in children aged 4 to 6 with cleft lip and palate before their bone graft surgery. The goal was to see if using the device before the operation would also reduce pain and shorten hospit…
Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Symptom relief
Last updated Jun 27, 2026 07:51 UTC
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Cleft jaw surgery study cut short: did it help patients?
Knowledge-focused Stopped earlyThis study aimed to see if orthognathic (jaw) surgery improves quality of life for people born with cleft lip and palate. Researchers planned to compare questionnaire scores before and 6 months after surgery in about 10 participants. The study was terminated early, so results are…
Sponsor: University Hospital, Lille • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:35 UTC