Malignant urinary system neoplasm
MONDO:0006295A primary or metastatic malignant tumor involving the urinary system. Common tumor types include carcinomas, lymphomas, and sarcomas.
Also known as: cancer of renal system, malignant neoplasm of renal system, malignant renal system neoplasm, malignant urinary system neoplasm, malignant urinary tract neoplasm, renal system cancer, urinary system cancer
4271 clinical trials for this condition and its sub-types, 75 tagged with Malignant urinary system neoplasm itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Malignant urinary system neoplasm
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Kidney cancer 244 trials · 851 incl. sub-types
8 sub-types
- Renal carcinoma 85 trials · 764 incl. sub-types Sub-types →
- Childhood malignant kidney neoplasm 0 trials · 30 incl. sub-types Sub-types →
- Malignant renal pelvis neoplasm 6 trials · 23 incl. sub-types Sub-types →
- Kidney Wilms tumor 9 trials · 11 incl. sub-types Sub-types →
- Kidney sarcoma 0 trials · 8 incl. sub-types Sub-types →
- Mesoblastic nephroma 4 trials Sub-types →
- Graham-Boyle-Troxell syndrome 0 trials
- Malignant mixed epithelial stromal tumor of the kidney 0 trials
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Urothelial carcinoma 364 trials · 695 incl. sub-types
5 sub-types
- Bladder transitional cell carcinoma 131 trials · 411 incl. sub-types Sub-types →
- Renal pelvis/ureter urothelial carcinoma 65 trials · 78 incl. sub-types Sub-types →
- Urethra transitional cell carcinoma 17 trials Sub-types →
- Pure squamous carcinoma of the urothelial tract 1 trial
- Non-papillary transitional cell carcinoma of the bladder 0 trials
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Urinary bladder cancer 40 trials · 686 incl. sub-types
9 sub-types
- Urinary bladder carcinoma 394 trials · 673 incl. sub-types Sub-types →
- Urachus cancer 3 trials · 6 incl. sub-types Sub-types →
- Bladder dome cancer 0 trials Sub-types →
- Bladder lateral wall cancer 0 trials
- Bladder lymphoma 0 trials
- Bladder neck cancer 0 trials
- Bladder sarcoma 0 trials
- Urinary bladder anterior wall cancer 0 trials
- Urinary bladder posterior wall cancer 0 trials
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Infiltrating urothelial carcinoma 5 trials · 187 incl. sub-types
2 sub-types
- Infiltrating bladder urothelial carcinoma 183 trials · 185 incl. sub-types Sub-types →
- Infiltrating renal pelvis/ureter urothelial carcinoma 2 trials Sub-types →
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Ureter cancer 27 trials · 34 incl. sub-types
3 sub-types
- Ureter carcinoma 1 trial · 19 incl. sub-types Sub-types →
- Ureteral lymphoma 0 trials
- Ureteric orifice cancer 0 trials
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Urethra cancer 18 trials · 29 incl. sub-types
5 sub-types
- Carcinoma of urethra 2 trials · 21 incl. sub-types Sub-types →
- Anterior urethra cancer 0 trials
- Female urethral cancer 0 trials
- Male urethral cancer 0 trials Sub-types →
- Posterior urethra cancer 0 trials
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Multiple endocrine neoplasia type 2B 2 trials
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Malignant prostate phyllodes tumor 0 trials
Most studied deeper sub-types
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New hope for HER2 cancers: targeted drug shows promise in Mid-Stage trial
Disease control CompletedThis phase 2 trial is testing a drug called ado-trastuzumab emtansine (Kadcyla) in 131 adults with advanced solid tumors that have a specific HER2 gene change. The drug combines an antibody that targets HER2 with a chemotherapy agent, aiming to deliver treatment directly to cance…
Phase 2 • Sponsor: Memorial Sloan Kettering Cancer Center • Aim: Disease control
Last updated Sep 11, 2026 00:00 UTC
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New surgical technique may help men regain bladder control faster after prostate cancer surgery
Disease control CompletedThis study compared two robot-assisted surgical techniques for removing the prostate in men with prostate cancer. One method uses a combined posterior-anterior-lateral (PAL) approach, while the other uses a traditional posterior approach. The goal was to see which technique leads…
Sponsor: The First Affiliated Hospital of Zhengzhou University • Aim: Disease control
Last updated Jun 27, 2026 08:07 UTC
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New scan could reveal cancer drug success in days, not months
Diagnosis CompletedThis pilot study tested a special PET scan method to see if it could detect early signs that targeted therapy is working for genitourinary cancer. Eleven patients had scans before and two weeks after starting treatment. The goal was to see if changes in tumor blood flow could pre…
Sponsor: University of California, Davis • Aim: Diagnosis
Last updated Jun 27, 2026 11:00 UTC
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A good Night's sleep for cancer patients? video therapy put to the test
Symptom relief CompletedThis pilot study explores whether cancer patients are willing to complete a quick self-screening for insomnia during clinic visits, and whether a video-based cognitive behavioral therapy (CBT-I) could help them sleep better. The study involves adults with breast, colorectal, lung…
Sponsor: Gustave Roussy, Cancer Campus, Grand Paris • Aim: Symptom relief
Last updated Aug 21, 2026 00:00 UTC
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Talking through cancer: can couples therapy ease the emotional toll?
Symptom relief CompletedThis study tested a program that teaches couples communication skills when one partner has advanced cancer. About 440 patients and their partners took part, with half receiving the training and half getting general healthy living information. The goal was to see if the training c…
Sponsor: Duke University • Aim: Symptom relief
Last updated Jun 27, 2026 08:13 UTC
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New phone therapy aims to ease anxiety in older cancer patients
Symptom relief CompletedThis study tested a telephone-based therapy called Managing Anxiety from Cancer (MAC) for older adults (65+) with cancer and their caregivers. The therapy includes seven sessions covering relaxation, communication, and problem-solving skills. The goal was to see if it reduces anx…
Sponsor: Memorial Sloan Kettering Cancer Center • Aim: Symptom relief
Last updated Jun 27, 2026 07:55 UTC
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Nurse video visits help cancer patients after hospital discharge
Symptom relief CompletedThis study tested a program called CONTINUUM, where advanced cancer patients had a video visit with an oncology nurse within three days of leaving the hospital. The goal was to help patients feel more confident managing their health and improve communication with their care team.…
Sponsor: Massachusetts General Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 07:52 UTC
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Sharper scans during radiation: a pilot study
Knowledge-focused CompletedThis study tested whether a new type of CT scan (dual energy CT) can produce clearer images of tumors during radiation therapy. Researchers compared the new scan to the standard scan in 30 adults receiving radiation for pelvic or genitourinary cancers. The goal was to see if the …
Sponsor: University of Michigan Rogel Cancer Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:08 UTC
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Scientists track Body's reaction to cancer immunotherapy
Knowledge-focused CompletedThis study looked at 98 adults with cancers like melanoma and lung cancer who were starting immunotherapy. Researchers measured inflammatory markers in their blood to understand how the body reacts to these drugs. The goal was to find ways to better manage side effects from treat…
Sponsor: Indiana University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:08 UTC
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Smart devices track cancer recovery at home
Knowledge-focused CompletedThis study tested whether using at-home monitoring devices (like a wristband pedometer, scale, and blood pressure cuff) can help improve care for cancer patients after they leave the hospital following surgery. 22 patients with various cancers participated. The goal was to see if…
Sponsor: City of Hope Medical Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:02 UTC
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Does fear of death push cancer patients toward aggressive treatment?
Knowledge-focused CompletedThis study looked at whether reminding people of their own mortality influences how aggressively they choose to treat urological cancer. Researchers surveyed 746 urologists and patients, asking them to imagine treatment scenarios after thinking about death. The goal was to unders…
Sponsor: Heinrich-Heine University, Duesseldorf • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:59 UTC