Large artery stroke

This study tests whether adding an interleukin-6 receptor inhibitor (a drug that reduces inflammation) to standard emergency stroke treatment helps people recover better after a severe stroke caused by a large blood clot in the front part of the brain. About 692 adults who are el…

This study looks at whether a procedure called endovascular treatment (EVT) can help people who have had a mild stroke caused by a blocked large artery in the brain. About 300 participants will either receive EVT plus standard medical care or standard care alone. The goal is to s…

This was a very early (Phase 1) study that planned to give a mixture of cold saline, minocycline, and magnesium directly into the brain's arteries right after a stroke procedure to reopen blocked vessels. The goal was to see if this cocktail could safely protect brain tissue and …

This study looked at 800 adults who had a stroke from a large blood clot in the brain. It compared a new device called the NeVa Stent Retriever to standard devices used to remove the clot. The goal was to see if the new device could restore blood flow better and with fewer side e…

Researchers are testing whether manual vagus nerve stimulation, a hands-on technique that targets the vagus nerve without surgery or electrical devices, can improve movement, autonomic function and thinking skills in people who had a stroke at least six months earlier. Participan…

Researchers in Finland are surveying about 2,000 adults who were treated for a stroke between 2020 and 2022 in two regions. The postal questionnaire asks about health, daily functioning, work and income, social inclusion, and experiences with social and health services. The goal …

This study looks at whether tiny RNA particles called exosomal microRNAs in the blood can act as a 'stroke clock' for people with a severe type of stroke caused by a blocked large artery in the front of the brain. Researchers will compare blood samples from stroke patients to hea…

This study follows over 2,400 adults in Korea who have had their first stroke. Researchers will track their recovery, daily activities, and quality of life for 10 years. The goal is to learn what factors help or hinder long-term recovery after a stroke.

This study looks at whether a coordinated emergency system, like those used for trauma, can help more severe stroke patients get a clot removal procedure called mechanical thrombectomy. Researchers will compare data from before and after the system is put in place across Alabama.…

This study looks at whether stopping overnight neurological checks in stroke patients can help prevent delirium, a common and serious complication. Researchers will compare patients who continue standard overnight checks with those who have them stopped, measuring rates of deliri…

This study follows 1000 adults who have had a stroke to better understand how the brain recovers. Researchers use brain scans, electrical signals, and physical tests to find patterns linked to recovery. The goal is to improve predictions and treatments for stroke survivors.

This study followed 602 people who had a stroke to see how many later had seizures. Researchers looked at blood tests, brain scans, and EEG recordings to find clues that might predict who is at risk. The goal is to better understand why some stroke survivors develop epilepsy.

This study looks at tandem stroke, a severe type of stroke caused by two blockages in series (one in a neck artery and one in a brain artery). Researchers will analyze data from about 2880 patients treated between 2018 and 2024 to identify risk factors and compare outcomes of dif…