Intestinal polyposis syndrome
MONDO:0015185A syndrome associated with the development of multiple polyps throughout the intestine. It includes familial adenomatous polyposis , hamartomatous polyposis syndromes, and other rare polyposis syndromes.
84 clinical trials for this condition and its sub-types, 3 tagged with Intestinal polyposis syndrome itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Intestinal polyposis syndrome
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Classic or attenuated familial adenomatous polyposis 0 trials · 35 incl. sub-types
8 sub-types
- Classic familial adenomatous polyposis 33 trials Sub-types →
- Attenuated familial adenomatous polyposis 3 trials Sub-types →
- Familial adenomatous polyposis 1 2 trials Sub-types →
- Polymerase proofreading-related adenomatous polyposis 1 trial Sub-types →
- Familial adenomatous polyposis 2 1 trial
- AXIN2-related attenuated familial adenomatous polyposis 0 trials
- Familial adenomatous polyposis 3 0 trials
- Familial adenomatous polyposis 4 0 trials
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Peutz-Jeghers syndrome 9 trials
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Hereditary mixed polyposis syndrome 5 trials · 6 incl. sub-types
2 sub-types
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Juvenile polyposis syndrome 5 trials
3 sub-types
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Cronkhite-Canada syndrome 1 trial
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Hyperplastic polyposis syndrome 1 trial
2 sub-types
- Colon serrated polyposis 1 trial
- Sessile serrated polyposis cancer syndrome 0 trials
Most studied deeper sub-types
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Promising Dup15q drug trial halted early
Disease control Stopped earlyThis study tested a drug called basmisanil in children aged 2 to 14 with Dup15q syndrome, a rare genetic condition that affects development. The goal was to see if the drug could improve daily living skills like communication and movement. The trial was stopped early after enroll…
Phase 2 • Sponsor: Hoffmann-La Roche • Aim: Disease control
Last updated Aug 20, 2026 00:00 UTC
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Could a liver drug tame polyps in rare gut condition?
Disease control Stopped earlyThis study tested whether obeticholic acid, a drug already used for liver disease, can safely reduce the number of polyps in the small bowel and colon in people with familial adenomatous polyposis (FAP). FAP is a rare genetic condition that greatly raises the risk of intestinal c…
Phase 2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Jun 27, 2026 12:33 UTC
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Study checks if stopping a drug made polyps grow faster
Knowledge-focused Stopped earlyThis study reviewed medical records of 42 people with familial adenomatous polyposis (FAP) who had previously taken the drug erlotinib. Researchers wanted to see how quickly the disease progressed after the drug was stopped. The goal was to better understand what happens when tre…
Sponsor: National Cancer Institute (NCI) • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:05 UTC