Intestinal polyposis syndrome
MONDO:0015185A syndrome associated with the development of multiple polyps throughout the intestine. It includes familial adenomatous polyposis , hamartomatous polyposis syndromes, and other rare polyposis syndromes.
84 clinical trials for this condition and its sub-types, 3 tagged with Intestinal polyposis syndrome itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Intestinal polyposis syndrome
-
Classic or attenuated familial adenomatous polyposis 0 trials · 35 incl. sub-types
8 sub-types
- Classic familial adenomatous polyposis 33 trials Sub-types →
- Attenuated familial adenomatous polyposis 3 trials Sub-types →
- Familial adenomatous polyposis 1 2 trials Sub-types →
- Polymerase proofreading-related adenomatous polyposis 1 trial Sub-types →
- Familial adenomatous polyposis 2 1 trial
- AXIN2-related attenuated familial adenomatous polyposis 0 trials
- Familial adenomatous polyposis 3 0 trials
- Familial adenomatous polyposis 4 0 trials
-
Peutz-Jeghers syndrome 9 trials
-
Hereditary mixed polyposis syndrome 5 trials · 6 incl. sub-types
2 sub-types
-
Juvenile polyposis syndrome 5 trials
3 sub-types
-
Cronkhite-Canada syndrome 1 trial
-
Hyperplastic polyposis syndrome 1 trial
2 sub-types
- Colon serrated polyposis 1 trial
- Sessile serrated polyposis cancer syndrome 0 trials
Most studied deeper sub-types
-
A deep-dive into gum disease: can a standard cleaning calm the body's tissue-damage signals?
Disease control Not yet recruitingThis trial looks at people who have both periodontitis (gum disease around natural teeth) and peri-implantitis (inflammation around dental implants). Researchers will measure three proteins in the fluid around teeth and implants before and after routine non-surgical therapy, whic…
Sponsor: Adiyaman University • Aim: Disease control
Last updated Sep 03, 2026 00:00 UTC
-
Can an experimental drug stop polyps from coming back in a rare inherited condition?
Disease control Not yet recruitingThis phase 1b trial tests an experimental drug called ST316 in adults with familial adenomatous polyposis (FAP) who have already had their colon removed but still develop new polyps. The study aims to see if ST316 is safe and can reduce the number and size of polyps that grow bac…
Phase 1 • Sponsor: Sapience Therapeutics • Aim: Disease control
Last updated Aug 14, 2026 00:00 UTC
-
Could a cancer drug boost social abilities in rare genetic condition?
Disease control Not yet recruitingThis study tests whether everolimus, a drug already approved for other conditions, can safely improve social abilities in people with PTEN Hamartoma Tumor Syndrome (PHTS). About 60 adults and children with PHTS and social difficulties will take either everolimus or a placebo for …
Phase 2/3 • Sponsor: Boston Children's Hospital • Aim: Disease control
Last updated Jun 27, 2026 13:03 UTC
-
Could a common drug curb polyps in teens with rare genetic condition?
Disease control Not yet recruitingThis study tests two low doses of rapamycin, a drug usually used to prevent organ rejection, in 25 teenagers (ages 12-17) with familial adenomatous polyposis (FAP), a genetic condition that causes many colon polyps and raises cancer risk. The main goal is to see if the drug is sa…
Phase 2 • Sponsor: University Hospital, Toulouse • Aim: Disease control
Last updated Jun 27, 2026 12:30 UTC
-
New DNA sequencer could make genetic testing cheaper and faster
Diagnosis Not yet recruitingThis study compares a new DNA sequencing platform (MGI) against the current standard (Illumina) for diagnosing hereditary cancers like breast and ovarian cancer, Lynch syndrome, and intestinal polyposis. Researchers will analyze 248 patient samples using both platforms to see if …
Sponsor: Fondazione Policlinico Universitario Agostino Gemelli IRCCS • Aim: Diagnosis
Last updated Jun 26, 2026 14:56 UTC
-
Scientists map cellular secrets of recurring colon polyps to prevent future cancer
Knowledge-focused Not yet recruitingThis study investigates why colorectal adenomas (precancerous polyps) sometimes return after being surgically removed. Researchers will collect tissue samples from 30 patients and use advanced genetic sequencing to compare polyps that recur with those that do not. The goal is to …
Sponsor: Zhongshan Hospital Xiamen University • Aim: Knowledge-focused
Last updated Jul 08, 2026 00:00 UTC
-
New online tool aims to help families uncover hidden cancer risks
Knowledge-focused Not yet recruitingThis study tests whether a new online program can help families understand their inherited cancer risk and encourage relatives to get low-cost genetic testing. Researchers will enroll 400 adults who carry a cancer-related gene change and their family members. The goal is to see i…
Sponsor: Stanford University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:33 UTC
-
Simple Pre-Surgery steps could boost stoma Patients' quality of life
Knowledge-focused Not yet recruitingThis study will follow 100 people who need a stoma (an opening in the belly to pass stool) after surgery. Some will have their stoma site marked and get education before surgery, while others will not. The goal is to see if these steps improve quality of life and reduce problems …
Sponsor: Assistance Publique Hopitaux De Marseille • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:57 UTC