Inherited primary ovarian failure
MONDO:0019852An instance of primary ovarian failure that is caused by an inherited modification of the individual's genome.
Also known as: hereditary primary ovarian failure, inherited POI, inherited premature ovarian failure, inherited primary ovarian insufficiency, non-acquired premature ovarian failure
52 clinical trials for this condition and its sub-types, 2 tagged with Inherited primary ovarian failure itself.
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Sub-types of Inherited primary ovarian failure
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Turner syndrome 28 trials
3 sub-types
- Turner syndrome due to structural X chromosome anomalies 0 trials
- Mixed gonadal dysgenesis 0 trials
- Monosomy X 0 trials Sub-types →
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Ataxia telangiectasia 11 trials
1 sub-type
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Classic galactosemia 3 trials
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Trisomy X 3 trials
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46 XX gonadal dysgenesis 1 trial
11 sub-types
- SERKAL syndrome 0 trials
- Ovarian dysgenesis 1 0 trials
- Ovarian dysgenesis 10 0 trials
- Ovarian dysgenesis 11 0 trials
- Ovarian dysgenesis 2 0 trials
- Ovarian dysgenesis 3 0 trials
- Ovarian dysgenesis 5 0 trials
- Ovarian dysgenesis 6 0 trials
- Ovarian dysgenesis 7 0 trials
- Ovarian dysgenesis 8 0 trials
- Ovarian dysgenesis 9 0 trials
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Premature ovarian failure 1 1 trial
1 sub-type
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Perrault syndrome 0 trials
7 sub-types
- Perrault syndrome 1 0 trials
- Perrault syndrome 2 0 trials
- Perrault syndrome 3 0 trials
- Perrault syndrome 4 0 trials
- Perrault syndrome 5 0 trials
- Perrault syndrome 6 0 trials
- Perrault syndrome 7 0 trials
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Satoyoshi syndrome 0 trials
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X small rings 0 trials
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Aromatase deficiency 0 trials
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5 sub-types
- Blepharophimosis-epicanthus inversus-ptosis due to 3q23 rearrangement syndrome 0 trials
- Blepharophimosis-epicanthus inversus-ptosis due to a point mutation syndrome 0 trials
- Blepharophimosis-epicanthus inversus-ptosis due to copy number variations 0 trials
- Blepharophimosis-ptosis-epicanthus inversus syndrome type 1 0 trials
- Blepharophimosis-ptosis-epicanthus inversus syndrome type 2 0 trials
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Premature ovarian failure 10 0 trials
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Premature ovarian failure 11 0 trials
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Premature ovarian failure 12 0 trials
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Premature ovarian failure 13 0 trials
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Premature ovarian failure 14 0 trials
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Premature ovarian failure 15 0 trials
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Premature ovarian failure 16 0 trials
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Premature ovarian failure 17 0 trials
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Premature ovarian failure 18 0 trials
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Premature ovarian failure 19 0 trials
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Premature ovarian failure 20 0 trials
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Premature ovarian failure 21 0 trials
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Premature ovarian failure 22 0 trials
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Premature ovarian failure 23 0 trials
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Premature ovarian failure 24 0 trials
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Premature ovarian failure 25 0 trials
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Premature ovarian failure 26 0 trials
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Premature ovarian failure 2A 0 trials
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Premature ovarian failure 2B 0 trials
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Premature ovarian failure 3 0 trials
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Premature ovarian failure 4 0 trials
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Premature ovarian failure 5 0 trials
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Premature ovarian failure 6 0 trials
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Premature ovarian failure 7 0 trials
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Premature ovarian failure 8 0 trials
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Premature ovarian failure 9 0 trials
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Tetrasomy X 0 trials
Most studied deeper sub-types
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Continued EryDex treatment studied in rare neurological disorder
Disease control Stopped earlyThis study offered continued treatment with EryDex to 101 people with ataxia telangiectasia (A-T) who had finished a previous trial. The main goal was to monitor safety, including side effects and serious events. The study was terminated early, and it did not aim to cure the dise…
Phase 3 • Sponsor: Quince Therapeutics S.p.A. • Aim: Disease control
Last updated Jun 27, 2026 12:29 UTC
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Experimental drug shows promise for rare genetic disorder
Disease control Stopped earlyThis Phase II trial tested a drug called N-Acetyl-L-Leucine (IB1001) in 17 people with Ataxia-Telangiectasia, a rare genetic disease that affects movement and immunity. The study aimed to see if the drug could improve symptoms and slow the disease over time. The trial was termina…
Phase 2 • Sponsor: IntraBio Inc • Aim: Disease control
Last updated Jun 27, 2026 12:00 UTC
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Can sex boost the odds of IVF success?
Knowledge-focused Stopped earlyThis trial asks whether having sexual intercourse in the 72 hours after a frozen embryo transfer changes the likelihood of a clinical pregnancy. Researchers will compare pregnancy rates, miscarriage rates, and live birth rates between women who have sex and those who do not. The …
Sponsor: Fundación Santiago Dexeus Font • Aim: Knowledge-focused
Last updated Sep 10, 2026 00:00 UTC
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Ultrasound could uncover hidden vascular risks in turner syndrome
Knowledge-focused Stopped earlyThis study is looking at whether yearly ultrasound scans can detect blood vessel abnormalities throughout the body in women with Turner syndrome, not just in the heart area. Turner syndrome is a genetic condition that increases the risk of serious vascular problems, which can sho…
Sponsor: University Hospital, Strasbourg, France • Aim: Knowledge-focused
Last updated Aug 23, 2026 00:00 UTC