Gallstones
MONDO:0005346Solid crystalline precipitates in the biliary tract, usually formed in the gallbladder, resulting in the condition of cholelithiasis. Gallstones, derived from the bile, consist mainly of calcium, cholesterol, or bilirubin.
67 clinical trials for this condition and its sub-types, 36 tagged with Gallstones itself.
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Sub-types of Gallstones
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Choledocholithiasis 40 trials
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New drug may shorten jaundice in gallstone patients
Disease control CompletedThis study looked at whether a drug called Remaxol can help people with gallstones and a serious complication called obstructive jaundice. Obstructive jaundice happens when a gallstone blocks the bile duct, causing yellowing of the skin and eyes. The study involved 286 adults who…
Sponsor: POLYSAN Scientific & Technological Pharmaceutical Company • Aim: Disease control
Last updated Jun 27, 2026 12:23 UTC
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No-Surgery gallbladder fix shows promise in small trial
Disease control CompletedThis study tested a procedure called EUS-guided gallbladder drainage (EGBD) as an alternative to gallbladder removal surgery for 30 adults with acute cholecystitis (gallbladder inflammation). The goal was to see if it could safely resolve symptoms like fever and pain without need…
Sponsor: Chinese University of Hong Kong • Aim: Disease control
Last updated Jun 27, 2026 11:03 UTC
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New 'Smart' cut during ERCP aims to slash complication rates
Disease control CompletedThis study tested a new way to open the bile duct during an ERCP procedure. Instead of the standard pull-type cut, doctors used a special hooked knife (ASD) designed to cut only the circular muscle layer, potentially causing less damage. Over 1,500 patients were randomly assigned…
Sponsor: Military Medical Clinical Center of the Southern Region, Ukraine • Aim: Disease control
Last updated Jun 27, 2026 08:08 UTC
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Blood test may spot hidden gallbladder cancer in gallstone patients
Diagnosis CompletedThis study looks at whether ten specific substances in the blood can help tell apart patients with gallbladder cancer from those with only gallstone disease. Researchers will measure these markers in a new group of Chilean patients to confirm earlier findings. If the markers prov…
Sponsor: Centre Paul Strauss • Aim: Diagnosis
Last updated Aug 06, 2026 00:00 UTC
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Nature sounds may ease pain and stress after surgery, small study finds
Symptom relief CompletedThis study tested whether listening to nature sounds while walking after gallbladder surgery could reduce anxiety, pain, and stress. Seventy adults who had laparoscopic cholecystectomy took part. Patients walked 50 meters while hearing nature sounds, then returned to bed. Their a…
Sponsor: Akdeniz University • Aim: Symptom relief
Last updated Jun 27, 2026 12:31 UTC
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No-Clip gallbladder surgery shows promise in small trial
Symptom relief CompletedThis study tested a new way to remove the gallbladder using a harmonic scalpel instead of metal clips to seal blood vessels and bile ducts. The trial involved 158 adults with gallstones who were scheduled for elective surgery. The goal was to see if the clipless method reduces su…
Sponsor: Services Hospital, Lahore • Aim: Symptom relief
Last updated Jun 27, 2026 11:01 UTC
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Simple video before discharge may boost gallbladder surgery recovery
Symptom relief CompletedThis study tested whether showing patients a 10-15 minute video about post-surgery care (pain, diet, wound care, warning signs) before they leave the hospital helps them recover better after laparoscopic gallbladder removal. 92 adults took part, with half getting the video plus u…
Sponsor: Izmir Tinaztepe University • Aim: Symptom relief
Last updated Jun 27, 2026 08:03 UTC
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Shock therapy for surgery pain? TENS device tested after gallbladder removal
Symptom relief CompletedThis study tested whether a TENS device (which sends mild electrical pulses through the skin) can help people recover after laparoscopic gallbladder removal. 140 adults were randomly assigned to receive TENS or standard care in the first 24 hours after surgery. Researchers measur…
Sponsor: Cukurova University • Aim: Symptom relief
Last updated Jun 26, 2026 16:15 UTC
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Gut bacteria may predict gallbladder cancer in south american patients
Knowledge-focused CompletedThis study looked at whether the amount of three types of bacteria in stool samples is linked to gallbladder cancer risk. Researchers compared 230 South American patients with gallstones, some who had gallbladder cancer and some who did not. The goal was to confirm earlier findin…
Sponsor: Centre Paul Strauss • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:07 UTC
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Gut bacteria may predict gallbladder cancer in gallstone patients
Knowledge-focused CompletedThis study looked at 120 South American patients with gallstones to confirm if certain bacteria in stool are linked to gallbladder cancer risk. Researchers measured three types of gut bacteria using advanced DNA sequencing. The goal was to validate earlier findings that these bac…
Sponsor: Centre Paul Strauss • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:04 UTC
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Ultrasound vs. reality: can scans predict tough gallbladder surgeries?
Knowledge-focused CompletedThis study looked at 130 patients with gallstones who had their gallbladder removed by keyhole surgery. Researchers compared the ultrasound results done before surgery with what the surgeon actually found during the operation. The goal was to see if ultrasound can predict when th…
Sponsor: Nepal Medical College and Teaching Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:07 UTC
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Pandemic Didn't stop this gallstone surgery from working
Knowledge-focused CompletedThis study looked at 237 patients who had a single surgery to remove both their gallbladder and any gallstones stuck in the bile duct. Researchers wanted to see if the COVID-19 pandemic changed how safe or effective this procedure was. They found that the surgery remained a good …
Sponsor: Imperial College London • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:00 UTC
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New stitching method may speed up gallstone surgery
Knowledge-focused CompletedThis study looked at 360 patients who had gallstone removal surgery with a T-tube drain. Doctors compared a new continuous stitching method to the traditional interrupted stitch for closing the bile duct. The goal was to see which method is faster and just as safe. Results could …
Sponsor: Yantai Affiliated Hospital of Binzhou Medical University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:11 UTC
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Deep sleep or light nod? study probes best sedation for gallstone procedure
Knowledge-focused CompletedThis study looked at over 121,000 procedures to remove gallstones from the bile duct using a scope (ERCP). Researchers wanted to see if the level of sedation given during the procedure affected whether stones were left behind. They found that deeper sedation might help the doctor…
Sponsor: Karolinska Institutet • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:53 UTC
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Vegetarian diet linked to lower risk of dementia, heart disease, and more in massive study
Knowledge-focused CompletedThis completed study followed over 18,000 Taiwanese Buddhists to see if a vegetarian diet is linked to a lower risk of chronic diseases like dementia, depression, heart disease, stroke, gout, cataracts, gallstones, and urinary tract infections. Researchers compared health records…
Sponsor: Dalin Tzu Chi General Hospital • Aim: Knowledge-focused
Last updated Jun 26, 2026 15:57 UTC