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Blood test may spot hidden gallbladder cancer in gallstone patients

NCT ID NCT07744477

Diagnosis Sponsor: Centre Paul Strauss Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 04, 2026 · Last updated Aug 05, 2026 · Updated 1 time

Summary

This study looks at whether ten specific substances in the blood can help tell apart patients with gallbladder cancer from those with only gallstone disease. Researchers will measure these markers in a new group of Chilean patients to confirm earlier findings. If the markers prove reliable, they might one day be used as a simple blood test to catch gallbladder cancer earlier.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
serum samples
What this could lead to
If validated, these blood markers could lead to a simple blood test to help detect gallbladder cancer earlier in people with gallstones.
What could go wrong
This is a validation study, so the markers may not hold up in a larger, independent group. Also, the findings may not apply to patients outside South America.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

230 people

The number who actually took part.

Started

Dec 2019

Finished

Jan 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Patients with gallstones and cancer-free OR - Patients with gallbladder cancer

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients with gallstones and cancer-free OR - Patients with gallbladder cancer * Patients aged 18 years or older Exclusion Criteria: • Patients younger than 18 years

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Conditions

The condition(s) this trial relates to.

cholelithiasis gallbladder cancer gallbladder neoplasm gallstones

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Gallbladder malignant neoplasm Gallstone disease

Contacts and locations

Locations

  • Clínica Alemana de Santiago

    Santiago, Chile

  • Clínica Alemana de Temuco

    Temuco, Chile

  • Clínica Monte Sinaí

    Juliaca, Peru

  • Complejo Asistencial Padre Las Casas

    Temuco, Chile

  • Complejo Hospitalario Viedma

    Cochabamba, Bolivia

  • Fundación Arturo López Perez (FALP)

    Santiago, Chile

  • Hospital Barros Luco

    Santiago, Chile

  • Hospital Base III- La Capilla ESSALUD

    Juliaca, Peru

  • Hospital Clínico Universidad de Chile

    Santiago, Chile

  • Hospital Clínico de Magallanes

    Arica, Chile

  • Hospital De Puerto Montt

    Port Montt, Chile

  • Hospital El Pino

    Santiago, Chile

  • Hospital Goyoneche

    Arequipa, Peru

  • Hospital Honorio Delgado

    Arequipa, Peru

  • Hospital Obrero No. 2 (Caja Nacional del Seguro Social)

    Cochabamba, Bolivia

  • Hospital Padre Hurtado

    Santiago, Chile

  • Hospital Regional Manuel Nuñez Butrón

    Puno, Peru

  • Hospital Regional de Arica

    Arica, Chile

  • Hospital Regional de Concepción,

    Concepción, Chile

  • Hospital Regional de Rancagua

    Rancagua, Chile

  • Hospital Regional de Talca

    Talca, Chile

  • Hospital Regional de Temuco

    Temuco, Chile

  • Hospital San Borja

    Santiago, Chile

  • Hospital San Juan de Dios

    Santiago, Chile

  • Hospital Sótero del Río

    Santiago, Chile

  • Hospital del Norte

    Cochabamba, Bolivia

  • Hospital del Salvador

    Santiago, Chile

  • Instituto Gastroenterológico

    Cochabamba, Bolivia

  • Instituto Nacional de Enfermedades Neoplásicas (INEN)

    Lima, Peru

  • Instituto Oncológico Nacional

    Cochabamba, Bolivia

  • Instituto Regional de Enfermedades Neoplásicas del Norte (IREN Norte)

    Trujillo, Peru

  • Instituto Regional de Enfermedades Neoplásicas del Sur (IREN Sur)

    Arequipa, Peru

  • Statistical Genetics Research Group, Institute of Medical Biometry, University of Heidelberg

    Heidelberg, Germany

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