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Gut bacteria may predict gallbladder cancer in gallstone patients

NCT ID NCT07635745

Knowledge-focused Sponsor: Centre Paul Strauss Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at 120 South American patients with gallstones to confirm if certain bacteria in stool are linked to gallbladder cancer risk. Researchers measured three types of gut bacteria using advanced DNA sequencing. The goal was to validate earlier findings that these bacteria may signal higher cancer risk. No treatment was given; this was an observational study to better understand the connection.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If confirmed, this could help identify gallstone patients at higher risk for gallbladder cancer, enabling earlier monitoring or prevention.
What could go wrong
This is an observational validation study, not a treatment trial. The findings may not lead to immediate clinical changes and need further research.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

120 people

The number who actually took part.

Started

Dec 2019

Finished

Jan 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

\- Patients with gallstones and cancer-free OR - Patients with gallbladder cancer

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients with gallstones and cancer-free OR - Patients with gallbladder cancer Exclusion Criteria: * Antibiotics use

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Conditions

The condition(s) this trial relates to.

gallbladder cancer gallbladder neoplasm gallstones

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Gallbladder malignant neoplasm

Contacts and locations

Locations

  • Caja Nacional de Seguro Social Cochabamba, Complejo Hospitalario Viedma, Instituto Gastroenterológico

    Cochabamba, Bolivia

  • Hospital Dr. Hernán Henriquez Aravena, Complejo Asistencial Padre las Casas, Hospital Regional de Talca, Hospital Regional de Concepción, Hospital Regional de Arica

    Talca, Chile

  • Instituto Regional de Enfermedades Neoplasicas del Sur (IREN SUR), Hospital Regional Honorio Delgado Espinoza, Hospital Goyeneche Arequipa, Hospital Regional Manuel Nuñez Butron-Puno

    Arequipa, Peru

  • Statistical Genetics Research Group, Institute of Medical Biometry, University of Heidelberg

    Heidelberg, Germany

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