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Gut bacteria may predict gallbladder cancer in gallstone patients

NCT ID NCT07635745

First seen Jun 10, 2026 · Last updated Jun 23, 2026 · Updated 1 time

Summary

This study looked at 120 South American patients with gallstones to confirm if certain bacteria in stool are linked to gallbladder cancer risk. Researchers measured three types of gut bacteria using advanced DNA sequencing. The goal was to validate earlier findings that these bacteria may signal higher cancer risk. No treatment was given; this was an observational study to better understand the connection.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Caja Nacional de Seguro Social Cochabamba, Complejo Hospitalario Viedma, Instituto Gastroenterológico

    Cochabamba, Bolivia

  • Hospital Dr. Hernán Henriquez Aravena, Complejo Asistencial Padre las Casas, Hospital Regional de Talca, Hospital Regional de Concepción, Hospital Regional de Arica

    Talca, Chile

  • Instituto Regional de Enfermedades Neoplasicas del Sur (IREN SUR), Hospital Regional Honorio Delgado Espinoza, Hospital Goyeneche Arequipa, Hospital Regional Manuel Nuñez Butron-Puno

    Arequipa, Peru

  • Statistical Genetics Research Group, Institute of Medical Biometry, University of Heidelberg

    Heidelberg, Germany

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If confirmed, this could help identify gallstone patients at higher risk for gallbladder cancer, enabling earlier monitoring or prevention.

What could go wrong

This is an observational validation study, not a treatment trial. The findings may not lead to immediate clinical changes and need further research.

Conditions

The condition(s) this trial relates to.

gallbladder cancer Gallbladder Neoplasms

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.