Familial dilated cardiomyopathy
MONDO:0016333A a genetic form of heart disease that occurs when heart (cardiac) muscle becomes thin and weakened in at least one chamber of the heart, causing the open area of the chamber to become enlarged (dilated). As a result, the heart is unable to pump blood as efficiently as usual. To compensate, the heart attempts to increase the amount of blood being pumped through the heart, leading to further thinning and weakening of the cardiac muscle. Over time, this condition results in heart failure.
Also known as: hereditary dilated cardiomyopathy, DCM, dilated cardiomyopathy, familial, hypokinetic dilated cardiomyopathy, familial, idiopathic dilated cardiomyopathy
69 clinical trials for this condition and its sub-types, 7 tagged with Familial dilated cardiomyopathy itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Familial dilated cardiomyopathy
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Leber hereditary optic neuropathy 18 trials
1 sub-type
- Leber optic atrophy and dystonia 0 trials
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Familial isolated dilated cardiomyopathy 0 trials · 11 incl. sub-types
45 sub-types
- Dilated cardiomyopathy 1HH 5 trials
- Dilated cardiomyopathy 1A 2 trials
- Dilated cardiomyopathy 1C 1 trial
- Dilated cardiomyopathy 1FF 1 trial
- Dilated cardiomyopathy 1P 1 trial
- Dilated cardiomyopathy 3B 1 trial
- Cardiomyopathy, dilated, 2D 0 trials
- Cardiomyopathy, dilated, 2E 0 trials
- Cardiomyopathy, dilated, 2F 0 trials
- Cardiomyopathy, dilated, 2G 0 trials
- Cardiomyopathy, dilated, 2H 0 trials
- Cardiomyopathy, dilated, 2c 0 trials
- Dilated cardiomyopathy 1AA 0 trials
- Dilated cardiomyopathy 1B 0 trials
- Dilated cardiomyopathy 1BB 0 trials
- Dilated cardiomyopathy 1CC 0 trials
- Dilated cardiomyopathy 1D 0 trials
- Dilated cardiomyopathy 1DD 0 trials
- Dilated cardiomyopathy 1E 0 trials
- Dilated cardiomyopathy 1EE 0 trials
- Dilated cardiomyopathy 1G 0 trials
- Dilated cardiomyopathy 1GG 0 trials
- Dilated cardiomyopathy 1H 0 trials
- Dilated cardiomyopathy 1I 0 trials
- Dilated cardiomyopathy 1II 0 trials
- Dilated cardiomyopathy 1JJ 0 trials
- Dilated cardiomyopathy 1K 0 trials
- Dilated cardiomyopathy 1KK 0 trials
- Dilated cardiomyopathy 1L 0 trials
- Dilated cardiomyopathy 1M 0 trials
- Dilated cardiomyopathy 1NN 0 trials
- Dilated cardiomyopathy 1O 0 trials
- Dilated cardiomyopathy 1Q 0 trials
- Dilated cardiomyopathy 1R 0 trials
- Dilated cardiomyopathy 1S 0 trials
- Dilated cardiomyopathy 1U 0 trials
- Dilated cardiomyopathy 1V 0 trials
- Dilated cardiomyopathy 1W 0 trials
- Dilated cardiomyopathy 1X 0 trials
- Dilated cardiomyopathy 1Y 0 trials
- Dilated cardiomyopathy 1Z 0 trials
- Dilated cardiomyopathy 2A 0 trials
- Dilated cardiomyopathy 2B 0 trials
- Left ventricular noncompaction 10 0 trials
- Left ventricular noncompaction 8 0 trials
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Barth syndrome 5 trials
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Kearns-Sayre syndrome 5 trials
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Emery-Dreifuss muscular dystrophy 2 trials · 4 incl. sub-types
4 sub-types
- Autosomal dominant Emery-Dreifuss muscular dystrophy 0 trials · 3 incl. sub-types Sub-types →
- X-linked Emery-Dreifuss muscular dystrophy 1 trial Sub-types →
- Emery-Dreifuss muscular dystrophy 3, autosomal recessive 0 trials
- Scapuloperoneal myopathy 0 trials Sub-types →
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Histiocytoid cardiomyopathy 3 trials
1 sub-type
- Cardiac lipidosis, familial 0 trials
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Cardiomyopathy, dilated, 100 0 trials
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Cardiomyopathy, dilated, 1LL 0 trials
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Cardiomyopathy, dilated, 1MM 0 trials
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Cardiomyopathy, dilated, 1QQ 0 trials
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Cardiomyopathy, dilated, 2I 0 trials
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Cardiomyopathy, dilated, 2K 0 trials
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Cardiomyopathy, dilated, 2M 0 trials
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Cardiomyopathy, dilated, 2j 0 trials
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Cardiomyopathy, dilated, 2l 0 trials
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Cardiomyopathy, dilated, 3C 0 trials
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Dilated cardiomyopathy 1J 0 trials
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Hypertrophic cardiomyopathy 25 0 trials
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Myofibrillar myopathy 1 0 trials
Most studied deeper sub-types
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Sugar supplement shows promise for rare disease in new trial
Disease control Not yet recruitingThis phase 2b trial tests AVTX-801, a D-galactose supplement, in 8 adults with PGM1-CDG, a rare genetic disorder affecting sugar metabolism. Participants currently on D-galactose will receive either the study drug or a placebo to see if it reduces disease-related events like low …
Phase 2 • Sponsor: Eva Morava-Kozicz • Aim: Disease control
Last updated Jun 27, 2026 11:01 UTC
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Could vitamin B3 save sight in rare genetic blindness?
Disease control Not yet recruitingThis early study tests whether high-dose vitamin B3 (nicotinamide) can help preserve or improve vision in people with Leber's hereditary optic neuropathy (LHON), a rare genetic disease that causes sudden vision loss. Researchers will give 13 participants 2 grams of vitamin B3 dai…
Phase 1 • Sponsor: University Hospital, Angers • Aim: Disease control
Last updated Jun 27, 2026 08:05 UTC
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New registry aims to improve care for muscular dystrophy patients
Knowledge-focused Not yet recruitingThis study is creating a registry for people with Duchenne and Becker muscular dystrophy, as well as symptomatic female carriers. The goal is to collect health data and quality-of-life information to monitor how new therapies work in real-world settings. Up to 1,500 participants …
Sponsor: Dr. Andreas Ziegler • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:05 UTC