Familial dilated cardiomyopathy

MONDO:0016333

A a genetic form of heart disease that occurs when heart (cardiac) muscle becomes thin and weakened in at least one chamber of the heart, causing the open area of the chamber to become enlarged (dilated). As a result, the heart is unable to pump blood as efficiently as usual. To compensate, the heart attempts to increase the amount of blood being pumped through the heart, leading to further thinning and weakening of the cardiac muscle. Over time, this condition results in heart failure.

Also known as: hereditary dilated cardiomyopathy, DCM, dilated cardiomyopathy, familial, hypokinetic dilated cardiomyopathy, familial, idiopathic dilated cardiomyopathy

69 clinical trials for this condition and its sub-types, 7 tagged with Familial dilated cardiomyopathy itself.

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Where it sits in the disease tree

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↑ Familial cardiomyopathy (219) ↑ Dilated cardiomyopathy (132)

Sub-types of Familial dilated cardiomyopathy

Leber hereditary optic neuropathy 18 trials
1 sub-type
- Leber optic atrophy and dystonia 0 trials
Familial isolated dilated cardiomyopathy 0 trials · 11 incl. sub-types
45 sub-types
- Dilated cardiomyopathy 1HH 5 trials
- Dilated cardiomyopathy 1A 2 trials
- Dilated cardiomyopathy 1C 1 trial
- Dilated cardiomyopathy 1FF 1 trial
- Dilated cardiomyopathy 1P 1 trial
- Dilated cardiomyopathy 3B 1 trial
- Cardiomyopathy, dilated, 2D 0 trials
- Cardiomyopathy, dilated, 2E 0 trials
- Cardiomyopathy, dilated, 2F 0 trials
- Cardiomyopathy, dilated, 2G 0 trials
- Cardiomyopathy, dilated, 2H 0 trials
- Cardiomyopathy, dilated, 2c 0 trials
- Dilated cardiomyopathy 1AA 0 trials
- Dilated cardiomyopathy 1B 0 trials
- Dilated cardiomyopathy 1BB 0 trials
- Dilated cardiomyopathy 1CC 0 trials
- Dilated cardiomyopathy 1D 0 trials
- Dilated cardiomyopathy 1DD 0 trials
- Dilated cardiomyopathy 1E 0 trials
- Dilated cardiomyopathy 1EE 0 trials
- Dilated cardiomyopathy 1G 0 trials
- Dilated cardiomyopathy 1GG 0 trials
- Dilated cardiomyopathy 1H 0 trials
- Dilated cardiomyopathy 1I 0 trials
- Dilated cardiomyopathy 1II 0 trials
- Dilated cardiomyopathy 1JJ 0 trials
- Dilated cardiomyopathy 1K 0 trials
- Dilated cardiomyopathy 1KK 0 trials
- Dilated cardiomyopathy 1L 0 trials
- Dilated cardiomyopathy 1M 0 trials
- Dilated cardiomyopathy 1NN 0 trials
- Dilated cardiomyopathy 1O 0 trials
- Dilated cardiomyopathy 1Q 0 trials
- Dilated cardiomyopathy 1R 0 trials
- Dilated cardiomyopathy 1S 0 trials
- Dilated cardiomyopathy 1U 0 trials
- Dilated cardiomyopathy 1V 0 trials
- Dilated cardiomyopathy 1W 0 trials
- Dilated cardiomyopathy 1X 0 trials
- Dilated cardiomyopathy 1Y 0 trials
- Dilated cardiomyopathy 1Z 0 trials
- Dilated cardiomyopathy 2A 0 trials
- Dilated cardiomyopathy 2B 0 trials
- Left ventricular noncompaction 10 0 trials
- Left ventricular noncompaction 8 0 trials
Barth syndrome 5 trials
Kearns-Sayre syndrome 5 trials
Autosomal recessive limb-girdle muscular dystrophy type 2E 5 trials
Autosomal recessive limb-girdle muscular dystrophy type 2C 4 trials
Symptomatic form of muscular dystrophy of Duchenne and Becker in female carriers 4 trials
Emery-Dreifuss muscular dystrophy 2 trials · 4 incl. sub-types
4 sub-types
- Autosomal dominant Emery-Dreifuss muscular dystrophy 0 trials · 3 incl. sub-types Sub-types →
- X-linked Emery-Dreifuss muscular dystrophy 1 trial Sub-types →
- Emery-Dreifuss muscular dystrophy 3, autosomal recessive 0 trials
- Scapuloperoneal myopathy 0 trials Sub-types →
Autosomal recessive limb-girdle muscular dystrophy type 2D 3 trials
Histiocytoid cardiomyopathy 3 trials
1 sub-type
- Cardiac lipidosis, familial 0 trials
Autosomal recessive limb-girdle muscular dystrophy type 2F 2 trials
PGM1-congenital disorder of glycosylation 1 trial
Autosomal recessive limb-girdle muscular dystrophy type 2M 1 trial
Autosomal recessive limb-girdle muscular dystrophy type 2W 1 trial
Early-onset myopathy with fatal cardiomyopathy 1 trial
DK1-congenital disorder of glycosylation 0 trials
Cardiomyopathy, dilated, 100 0 trials
Cardiomyopathy, dilated, 1LL 0 trials
Cardiomyopathy, dilated, 1MM 0 trials
Cardiomyopathy, dilated, 1QQ 0 trials
Cardiomyopathy, dilated, 2I 0 trials
Cardiomyopathy, dilated, 2K 0 trials
Cardiomyopathy, dilated, 2M 0 trials
Cardiomyopathy, dilated, 2j 0 trials
Cardiomyopathy, dilated, 2l 0 trials
Cardiomyopathy, dilated, 3C 0 trials
Dilated cardiomyopathy 1J 0 trials
Hypertrophic cardiomyopathy 25 0 trials
Myofibrillar myopathy 1 0 trials

Most studied deeper sub-types

Emery-Dreifuss muscular dystrophy 2, autosomal dominant (3) Congenital myopathy 7A, myosin storage, autosomal dominant (0) Emery-Dreifuss muscular dystrophy 1, X-linked (0) Emery-Dreifuss muscular dystrophy 4, autosomal dominant (0) Emery-Dreifuss muscular dystrophy 5, autosomal dominant (0) Emery-Dreifuss muscular dystrophy 6, X-linked (0) Emery-Dreifuss muscular dystrophy 7, autosomal dominant (0) X-linked myopathy with postural muscle atrophy (0) X-linked scapuloperoneal muscular dystrophy (0)

Including sub-types (69) Tagged with Familial dilated cardiomyopathy (7)

Trials to join now! 36 Not yet recruiting 3 Not yet finished but already full! 16 Completed 12 Terminated 2

Familial dilated cardiomyopathy

Where it sits in the disease tree

Most studied deeper sub-types

Experimental gene therapy for rare muscle disease shows early promise but study halted

Experimental gene therapy tested for rare muscular dystrophy