Decubitus ulcer

This study will test hyperbaric oxygen therapy (HBOT) — breathing pure oxygen in a pressurized chamber — for over 30 conditions, including long COVID, Crohn's disease, frostbite, and multiple sclerosis. Researchers will track 100 patients to see if HBOT improves their quality of …

This study compares how well pressure ulcers (bedsores) heal in older adults receiving care at home versus in a long-term care facility. It also looks at quality of life, patient satisfaction, and treatment costs. Eighty people aged 60 to 90 with stage II-IV pressure ulcers will …

This study looks at whether Jingwanhong Ointment, a traditional Chinese medicine applied to the skin, can safely and effectively treat pressure injuries (bedsores) in people who are bedridden long-term. Researchers will follow about 500 participants to measure how quickly wounds …

This trial tests whether a risk-based prevention bundle can lower the chance of pressure injuries in patients undergoing elective surgery lasting three hours or longer. Participants are assigned to receive either standard care or a bundle tailored to their individual risk level—l…

This pilot study tests whether adding manual lymphatic drainage (a gentle massage technique) to standard wound care can help heal pressure injuries (bedsores) in patients hospitalized in intensive care. The trial randomly assigns 60 adults with a pressure injury on the sacrum (ta…

This study tests whether a wound covering made from donated human placenta, called NeoThelium FT, helps heal chronic pressure ulcers (bedsores) better than standard care alone. About 148 adults with pressure ulcers on the pelvis or legs will be randomly assigned to receive either…

This Phase 3 trial will test whether a graft made from donated amniotic tissue can help heal chronic wounds like diabetic foot ulcers and venous leg ulcers better than standard care. About 600 adults with wounds that haven't healed in 4 weeks will take part. The study will measur…

This study tests an ointment called GM-XANTHO for treating stage II or III pressure ulcers (bedsores) in people with diabetes. About 58 participants will receive either a low or high dose of the ointment or a placebo, along with standard care. The goal is to see if the ointment h…

This trial tests whether a nursing care bundle created with the help of artificial intelligence can prevent medical device-related pressure injuries in intensive care patients. These injuries, which can be painful and serious, affect about 1 in 5 ICU patients. The study will comp…

This trial tests a modified way to position patients during neurosurgery under general anesthesia. The new method uses an L-shaped arm board and a funnel-shaped adhesive film to better distribute pressure and reduce nerve strain. Researchers will compare this with standard positi…

This study tests whether a silicone foam dressing placed over the breathing tube, along with regularly moving the tube, can prevent pressure injuries inside the mouth. It will involve 75 adults in intensive care who need a breathing machine. The goal is to find a simple way to pr…

This study tests whether placing soft foam dressings on the skin before heart surgery can prevent pressure injuries (bedsores). About 80 adults having long heart surgeries will be enrolled. Researchers will check for new skin injuries after surgery and track how severe they are. …

This study tests whether a gel made from aloe vera and peppermint can prevent pressure injuries (bedsores) in intensive care unit (ICU) patients. Forty adults who are at risk for bedsores will be randomly assigned to receive either the natural gel or standard hospital care. The m…

This study tests whether an ultrasound-based risk score can better predict and prevent pressure injuries (bedsores) in critically ill ICU patients. In phase 1, researchers will check how accurately the score identifies high-risk patients. In phase 2, some patients will receive nu…

This study tests whether a gel containing polyhexanide and biguanide can prevent biofilm (a tough layer of bacteria) from forming in pressure ulcers (bedsores). About 140 adults over 65 with stage II or III bedsores will receive the gel alone or with a special dressing. The goal …

This study tests a special air mattress that automatically turns ICU patients from side to side to prevent painful bedsores. Researchers will compare it to standard foam mattresses with manual turning by nurses. The goal is to see if the automatic mattress reduces nursing workloa…

This trial is testing a soft silicone foam dressing called Mepilex Up on adults with leg or foot ulcers and skin tears. The goal is to see if the dressing helps wounds progress toward healing and is safe to use. About 70 participants will use the dressing for up to 6 weeks, and d…

This study compares three lying positions (on your back, side, or stomach) before a routine injection into the buttock muscle. Researchers will measure pain, comfort, and satisfaction in 111 adults. The goal is to find the best position to make injections less uncomfortable.

This study compares three types of CPAP masks (binasal prong, nasal cannula, and nasal mask) to see which causes fewer nasal pressure injuries in preterm infants. 75 babies in the NICU will be randomly assigned to one mask type and monitored for 4 days. The goal is to find the ge…

This study tests whether playing a person's favorite music before and during wound care can reduce pain and help pressure injuries (bed sores) heal faster. Researchers will compare wound care with music to standard care without music in 50 older adults living in long-term care ho…

Pressure ulcers, also known as bedsores, are a serious risk for patients in intensive care. This study tests whether a standard severity score called SAPS 2 can predict which patients will develop these painful wounds. Researchers will follow 500 ICU patients, comparing the SAPS …

This registry study collects real-world data from about 300 adults treated with urinary bladder matrix (UBM) products for various wounds, including pressure ulcers, surgical incisions, and infections like Fournier's gangrene. Researchers track patient characteristics, treatment p…

This trial tests whether teaching pressure ulcer prevention with the Pecha Kucha technique, a fast-paced presentation style with 20 slides shown for 20 seconds each, helps nursing students identify ulcer stages and retain knowledge better than a standard PowerPoint lecture. Resea…

This study will test an artificial intelligence system that analyzes smartphone photos of hard-to-heal wounds to see if they are getting better, staying the same, or getting worse. Researchers will enroll 1,000 people with wounds that have not healed for over a month. The goal is…

This study aims to create a new questionnaire that measures how well nurses can prevent pressure injuries (also known as bedsores). Pressure injuries are a common problem in hospitals that can cause pain and longer stays. Researchers will test the questionnaire with 300 nurses in…

This study looks at how different positions and positioning devices affect pressure on areas like the heels, tailbone, elbows, and back of the head in burn patients. Researchers will use a special pressure-sensing mat to find which setups create the least pressure. The goal is to…

This study looks at how the skin barrier changes in intensive care patients who are at risk for pressure injuries (bedsores). Researchers will use non-invasive biosensors to measure things like skin moisture, acidity, and temperature in areas prone to bedsores. The goal is to und…

This study looks at whether operating room nurses who know more about pressure injuries caused by medical devices make better decisions in the operating room. About 165 nurses from three hospitals in Turkey will take a knowledge test and answer questions based on real-life scenar…

This study will see if using virtual care technologies in hospital units can reduce problems like patient falls, infections, and readmissions, while also improving patient satisfaction. About 10,000 adults admitted to six hospital units will take part, with three units using the …

This study tests whether training intensive care nurses in evidence-based practices can lower rates of ventilator-associated pneumonia, pressure ulcers, and central line bloodstream infections. Researchers will train nurses and use advanced equipment, then compare infection rates…

This study tests whether training nurses to follow evidence-based guidelines can reduce infections and other complications in intensive care units (ICUs) in low- and middle-income countries. About 50 nurses will be trained and their patients' outcomes compared to usual care. The …

This study will develop and test a digital twin-haptic mixed reality simulation to teach nursing students how to manage pressure injuries (bedsores). About 130 second-year nursing students will be randomly assigned to either the mixed reality simulation or a standard high-fidelit…