Congenital anomaly of cardiovascular system
MONDO:0024239A disease that has its basis in the disruption of cardiovascular system development.
Also known as: cardiovascular system development disease, congenital Abnormality of the circulatory system, congenital anomaly of cardiovascular system, congenital cardiovascular Abnormality, congenital cardiovascular anomaly, disorder of cardiovascular system development, congenital cardiovascular disorder
599 clinical trials for this condition and its sub-types, 5 tagged with Congenital anomaly of cardiovascular system itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Congenital anomaly of cardiovascular system
-
Congenital heart disease 269 trials · 419 incl. sub-types
23 sub-types
- Heart septal defect 3 trials · 94 incl. sub-types Sub-types →
- Tetralogy of fallot 34 trials
- Syndromic congenital heart disease 0 trials · 31 incl. sub-types Sub-types →
- Patent ductus arteriosus 28 trials Sub-types →
- Persistent truncus arteriosus 8 trials Sub-types →
- Coronary artery congenital malformation 3 trials · 4 incl. sub-types Sub-types →
- Congenital pulmonary veins anomaly 0 trials · 3 incl. sub-types Sub-types →
- Dextro-looped transposition of the great arteries 2 trials Sub-types →
- Structural congenital heart disease, multiple types - GATA4 0 trials · 1 incl. sub-types Sub-types →
- ACTC1-related distal arthrogryposis with congenital heart disease 0 trials
- GATA5-related congenital heart defects 0 trials Sub-types →
- GATA6-related congenital heart disease with or without pancreatic agenesis or neonatal diabetes 0 trials Sub-types →
- HAND1 related congenital heart defect 0 trials
- HAND2 related congenital heart defect 0 trials
- PLD1-related congenital heart disease 0 trials
- RBFOX2-related congenital heart disorder 0 trials
- TFAP2B-related congenital heart disease spectrum disorder 0 trials Sub-types →
- Aortic valve atresia 0 trials
- Congenital heart defects, multiple types 0 trials Sub-types →
- Heart defects-limb shortening syndrome 0 trials
- Mehta lewis patton syndrome 0 trials
- Mitral atresia disorder 0 trials
- Tricuspid atresia 0 trials
-
Congenital heart malformation 3 trials · 155 incl. sub-types
26 sub-types
- Congenital anomaly of the great arteries 1 trial · 72 incl. sub-types Sub-types →
- Conotruncal heart malformations 1 trial · 41 incl. sub-types Sub-types →
- Univentricular cardiopathy 14 trials · 38 incl. sub-types Sub-types →
- Transposition of the great arteries 10 trials · 11 incl. sub-types Sub-types →
- Congenital left-sided heart lesions 0 trials · 10 incl. sub-types Sub-types →
- Coronary artery congenital malformation 3 trials · 4 incl. sub-types Sub-types →
- Congenital mitral malformation 0 trials · 2 incl. sub-types Sub-types →
- Visceral heterotaxy 1 trial Sub-types →
- Laubry-Pezzi syndrome 0 trials
- Atrial septal aneurysm 0 trials
- Cardiac diverticulum 0 trials
- Congenital Gerbode defect 0 trials
- Congenital acardia 0 trials Sub-types →
- Congenital heart defects, multiple types, 1, X-linked 0 trials
- Congenital heart defects, multiple types, 2 0 trials
- Congenital pericardium anomaly 0 trials Sub-types →
- Congenital right-sided heart lesions 0 trials
- Criss-cross heart 0 trials
- Ectasia of the left appendage 0 trials
- Ectasia of the right atrial appendage 0 trials
- Ectopia cordis 0 trials
- Familial idiopathic dilatation of the right atrium 0 trials
- Interventricular septum aneurysm 0 trials
- Juxtaposition of the atrial appendages 0 trials
- Mesocardia 0 trials
- Triatrial heart 0 trials Sub-types →
-
Congenital arteriovenous fistula 60 trials · 61 incl. sub-types
2 sub-types
-
Venous hemangioma 17 trials
-
Persistent fetal circulation syndrome 11 trials
Most studied deeper sub-types
-
App-Based exercise program aims to strengthen hearts in congenital disease
Disease control Stopped earlyThis study tests a remote, app-enabled exercise program designed for people aged 10 to 50 with congenital heart disease. Participants use a smartphone app with exercise modules and wearable devices to track heart rate and progress. The goal is to see if this approach can safely i…
Sponsor: Duke University • Aim: Disease control
Last updated Aug 07, 2026 00:00 UTC
-
Experimental cell therapy takes on stubborn autoimmune diseases
Disease control Stopped earlyThis early study tested a new cell therapy called LUCAR-G79 in just 3 adults with severe autoimmune diseases that did not respond to standard treatments. The therapy uses specially engineered immune cells to target and potentially calm the overactive immune system. The main goals…
Phase 1 • Sponsor: Nanjing Legend Biotech Co. • Aim: Disease control
Last updated Jun 27, 2026 14:00 UTC
-
Heart drug study halted early: what we know
Disease control Stopped earlyThis study tested an experimental drug called CRD-4730 in people with a rare inherited heart rhythm disorder (CPVT) that can cause dangerous fast heartbeats. Seven adults received two different doses of the drug and a placebo to check safety and how the body processes it. The stu…
Phase 2 • Sponsor: Cardurion Pharmaceuticals, Inc. • Aim: Disease control
Last updated Jun 27, 2026 12:38 UTC
-
Abandoned study: can a common painkiller help close a tiny heart vessel in preemies?
Disease control Stopped earlyThis study tested whether adding acetaminophen to standard ibuprofen treatment could better close a blood vessel (ductus arteriosus) that stays open too long in very premature infants. The trial was planned for preterm babies born at or before 27 weeks and 6 days who needed breat…
Phase 2 • Sponsor: University of South Alabama • Aim: Disease control
Last updated Jun 27, 2026 12:26 UTC
-
Which heart device lead lasts longest in kids? study aims to find out
Disease control Stopped earlyThis study looked at two types of implantable cardioverter defibrillator (ICD) leads in children and patients with congenital heart disease. The goal was to see which lead type lasts longer without breaking and is easier to remove if needed. The trial was terminated early, so res…
Sponsor: Charles Berul • Aim: Disease control
Last updated Jun 27, 2026 11:02 UTC
-
Heart hole closure for migraines? tiny study halted early
Symptom relief Stopped earlyThis study tested whether closing a small hole in the heart (called a PFO) with a device could reduce migraine headaches. It planned to compare the real procedure to a sham (fake) procedure in adults aged 18-55 with frequent migraines. However, the study was stopped early after e…
Sponsor: W.L.Gore & Associates • Aim: Symptom relief
Last updated Jun 27, 2026 13:04 UTC
-
Can a brain zap and computer game sharpen aging minds?
Symptom relief Stopped earlyThis study tested whether combining a computer-based speed-of-processing training with a gentle electrical brain stimulation (alpha-tACS) could improve how quickly people with mild cognitive impairment process visual information. The trial planned to enroll 40 adults aged 65 and …
Sponsor: Portucalense University • Aim: Symptom relief
Last updated Jun 26, 2026 16:29 UTC
-
New MRI technique could make heart procedures safer and faster
Knowledge-focused Stopped earlyThis study tests whether special low-energy MRI settings can make it safe to use guidewires during heart catheterization. Guidewires help position catheters but can heat up in standard MRI. Researchers will enroll 22 adults who need a right heart catheterization to see if this ap…
Sponsor: National Heart, Lung, and Blood Institute (NHLBI) • Aim: Knowledge-focused
Last updated Jul 17, 2026 00:00 UTC
-
Dopamine may unclog lymphatic system in rare heart complication
Knowledge-focused Stopped earlyThis study looks at whether dopamine can improve lymph flow in people who developed protein-losing enteropathy (PLE) after Fontan surgery for single-ventricle heart disease. PLE is a serious complication where proteins leak into the gut, possibly due to poor lymphatic function. R…
Sponsor: University of Michigan • Aim: Knowledge-focused
Last updated Jul 16, 2026 00:00 UTC
-
Wireless heart monitor for infants tested, but study ends early
Knowledge-focused Stopped earlyThis study aimed to see if a wireless sensor could collect health information from babies with heart defects at home, replacing wired devices. Only 2 infants were enrolled before the study was stopped. The goal was to understand if the wireless device was easy to use and worked w…
Sponsor: Ann & Robert H Lurie Children's Hospital of Chicago • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:56 UTC
-
Tiny trial tests best way to create dialysis access
Knowledge-focused Stopped earlyThis pilot study aimed to compare two standard surgical methods for creating an arteriovenous (AV) fistula in the arm for dialysis patients with kidney failure. The goal was to see if a single procedure or two separate procedures leads to better outcomes and quality of life. Howe…
Sponsor: Tze-Woei Tan • Aim: Knowledge-focused
Last updated Jun 26, 2026 16:22 UTC