Childhood-onset schizophrenia

This study tests a 10-session program called AIM-AT, which uses acceptance-based techniques to help people with recent-onset psychosis better understand their illness and stick to their medication. The trial involves 126 participants in Hong Kong and tracks their medication adher…

This study is testing whether artificial intelligence can analyze a person's speech to help diagnose mental health conditions like depression, anxiety, autism, and schizophrenia. Researchers will record 500 people speaking and compare the AI's predictions to standard clinical dia…

This study tests whether virtual reality (VR) brain exercises can help people with schizophrenia or bipolar disorder think more clearly and function better in daily life. 80 adults will either receive VR training twice a week for 12 weeks or continue their usual care. Researchers…

This small pilot study tests whether adding brain-wave feedback (EEG) to virtual reality therapy helps people with schizophrenia better tolerate and reduce distressing auditory hallucinations. Thirty adults with schizophrenia who hear voices will receive either VR therapy alone o…

This study tests whether a type of talk therapy called Cognitive Behavioral Therapy for Insomnia (CBT-I) can improve sleep and daily functioning in veterans who have both psychosis and insomnia. About 152 veterans are taking part. The goal is to see if better sleep leads to bette…

This study tests whether a combined aerobic and strength training program is feasible for adults with psychotic disorders. Forty participants will exercise for about an hour per session. Researchers will measure how many complete the program and track changes in fitness and stren…

This study uses a noninvasive brain stimulation technique called TMS, combined with brain scans, to understand working memory problems in people with early psychosis. Twenty participants will receive both active and placebo TMS to see how it affects brain activity and memory perf…

This study follows 600 mentally ill offenders in Italy and California over three years to compare two very different treatment systems. Italy uses community-based care, while California relies on long-term hospital stays. Researchers will track violence, recovery, and functioning…

This study is collecting DNA, brain scans, and other biological samples from 2,000 people with major depression, bipolar disorder, or psychotic disorders, as well as healthy volunteers. The goal is to better understand the physical and genetic factors behind these conditions, whi…