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Can VR and brain training quiet the voices? new study investigates

NCT ID NCT06628323

Symptom relief Sponsor: University Hospital Bispebjerg and Frederiksberg Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This small pilot study tests whether adding brain-wave feedback (EEG) to virtual reality therapy helps people with schizophrenia better tolerate and reduce distressing auditory hallucinations. Thirty adults with schizophrenia who hear voices will receive either VR therapy alone or VR combined with neurofeedback. The study focuses on whether the combined approach is feasible, acceptable, and shows signs of being more effective at easing symptoms and improving daily life.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 30 people

The number the study aims to enrol. It can still change while the study runs.

Started

Nov 2024

Expected to finish

May 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 65 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Ability to give informed consent 2. Age of 18-65 years 3. Diagnosis of schizophrenia spectrum disorder (ICD-10 codes: F20, F22-23; F25-29) 4. Symtoms of Auditory Verbal Hallucinations within at least the past 3 months (corresponding to SAPS score of 3 or more) 5. Identification of at least one dominant voice 6. No changes in antipsychotic medications four weeks prior to inclusion in the project 7. No planned changes in antipsychotic medication in the 12 weeks following inclusion in the project 8. A command of Danish or English sufficient to engage in therapy Exclusion Criteria: 1. Rejecting informed consent 2. A diagnosis of organic brain disease 3. Intellectual disability (IQ ˂ 70) 4. A primary diagnosis of substance dependence hindering engaging in therapy 5. Hear voices in a language the therapist does not speak 6. Inability to tolerate the therapy

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Conditions

The condition(s) this trial relates to.

Hallucinations schizophrenia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Auditory hallucinations Schizophrenia

Contacts and locations

Locations

  • Copenhagen Research Center for Mental Health - CORE

    Copenhagen, Hellerup, 2900, Denmark

More trials for these conditions

Other studies related to the condition(s) this trial covers.