Cerebrospinal fluid leak
MONDO:0043327Discharge of cerebrospinal fluid through a hole through the skull bone most commonly draining from the nose (CEREBROSPINAL FLUID RHINORRHEA) or the ear (CEREBROSPINAL FLUID OTORRHEA).
Also known as: cerebrospinal fluid leak, CSF leak, CSF otorrhea, CSF rhinorrhea, Drainages, cerebrospinal fluid, Leakages, cerebrospinal fluid, Leaks, cerebrospinal fluid, cerebrospinal fluid Drainages
17 clinical trials for this condition and its sub-types, 16 tagged with Cerebrospinal fluid leak itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Cerebrospinal fluid leak
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Cerebrospinal fluid rhinorrhea 2 trials
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Can a dissolvable glue seal the brain and stop leaks after surgery?
Disease control CompletedThis clinical trial is testing whether a new absorbable adhesive can help seal the protective lining of the brain (the dura) after neurosurgery, preventing cerebrospinal fluid leaks. The study involves 132 adults who are having brain or spinal surgery and are at risk of such leak…
Phase 3 • Sponsor: Medprin Regenerative Medical Technologies Co., Ltd. • Aim: Disease control
Last updated Aug 19, 2026 00:00 UTC
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Can a glue stop spinal fluid leaks after surgery?
Disease control CompletedThis trial tests whether a special medical adhesive can create a watertight seal over the spinal lining after surgery, preventing cerebrospinal fluid leaks. About 141 adults undergoing spinal surgery with confirmed fluid leakage will be randomly assigned to receive either the adh…
Phase 3 • Sponsor: Medprin Regenerative Medical Technologies Co., Ltd. • Aim: Disease control
Last updated Aug 12, 2026 00:00 UTC
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Simple drain may prevent painful fluid pockets after hernia surgery
Disease control CompletedThis trial tests whether placing a temporary drain after laparoscopic inguinal hernia repair reduces the chance of seroma — a pocket of fluid that can cause swelling and discomfort. Half of the 48 participants receive a drain, the other half do not. Researchers track who develops…
Sponsor: Cairo University • Aim: Disease control
Last updated Jul 04, 2026 00:00 UTC
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New pillow eases leg vein symptoms overnight?
Symptom relief CompletedThis study tested whether sleeping with a special leg-elevation device (UZit®) can ease symptoms of chronic venous disease, a condition where leg veins have trouble moving blood back to the heart. Seventeen adults used the device every night for one week. Researchers measured cha…
Sponsor: Universidade do Porto • Aim: Symptom relief
Last updated Jun 27, 2026 08:03 UTC
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New study aims to improve drainage of pancreatic cysts
Knowledge-focused CompletedThis study looks at how doctors drain fluid-filled sacs called pancreatic pseudocysts that can form after severe pancreatitis. Researchers are observing 80 patients who get endoscopic ultrasound-guided drainage using either a plastic or metal stent. The goal is to see which metho…
Sponsor: Sahlgrenska University Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:24 UTC