Celiac disease

This early-phase study tests whether combining mesenchymal stem cells (MSCs) with specially engineered immune cells (CAR-T cells) is safe and can help control autoimmune diseases. About 30 adults with established autoimmune conditions will receive the treatment and be monitored f…

This study tests whether specially engineered immune cells, called CAR-T cells, can safely treat autoimmune diseases. The cells are designed to target and suppress B cells, which play a key role in many autoimmune conditions. The trial involves 30 adults and focuses on safety and…

This early-stage trial tests clonal fetal mesenchymal stem cells (cfMSCs) in 100 people with severe immune-related disorders or tissue damage. The goal is to see if the cells are safe and can reduce symptoms. Participants have no other treatment options left.

This early study tests an experimental drug called STR-P005 in people with autoimmune diseases that have come back or not improved with standard treatments. The drug is given through an IV in multiple doses. The main goal is to check safety and see how the body handles the drug. …

This early study tests a new drug called STR-P005 in 18 people with autoimmune diseases that have not responded to standard treatments. The main goal is to check safety and find the best dose. Participants receive the drug by infusion in different schedules, and researchers will …

This study tests whether blood samples collected at home using small capillary devices, like finger pricks, give the same results as traditional blood draws from a vein. Researchers will compare both methods in about 1,000 people with chronic conditions such as kidney disease, au…

This study aims to see if a blood test for TTG-IgA antibodies combined with symptom information can accurately sort adults into low, intermediate, or high risk for celiac disease. Researchers will analyze data from 15,500 patients who already had both a blood test and a duodenal …

This study tests a urine test that detects gluten peptides in children with celiac disease who are on a gluten-free diet. The goal is to see if this test helps doctors and families identify accidental gluten exposure better than standard blood tests. One hundred children aged 2 t…

This study aims to translate and validate the Celiac Dietary Adherence Test (CDAT) for Polish children with celiac disease. Researchers will enroll 20 participants aged 2 to 18, along with their caregivers, to check if the Polish version accurately measures how well they follow a…

This trial investigates whether annual re-screening for tuberculosis infection using a blood test (IGRA) can prevent active TB in people with autoimmune rheumatic diseases who are taking biologic or immunosuppressive medications. Participants who initially test negative for TB ar…

This study tests whether a single dose of amoxicillin before a simple tooth extraction can prevent infections in people with autoimmune rheumatic diseases who are on immune-suppressing medications. Researchers will compare infection rates between those who get the antibiotic and …

This study asks whether drinking kefir every day can reduce gastrointestinal symptoms and improve quality of life in adults with celiac disease who follow a strict gluten-free diet. In a crossover design, 30 participants will consume 200 mL of kefir daily for four weeks, then con…

This study looks at whether a gluten-free diet can reduce inflammatory back pain. Researchers will split 50 people into two groups: one gets standard treatment, the other adds a gluten-free diet for a year. They'll measure pain levels and immune markers to see if the diet makes a…

This study looks at whether children with celiac disease may have a higher risk of heart rhythm problems compared to healthy children. Researchers will measure specific heart rhythm intervals using an ECG in children diagnosed with celiac disease and compare them to healthy child…

This study explores whether a simple ultrasound and a blood test can track celiac disease activity, potentially replacing the need for invasive intestinal biopsies. Researchers will scan the small bowel and measure antibody levels in 140 people, including newly diagnosed patients…

This study will test a new way to offer vaccines to vulnerable patients—those with chronic diseases or weakened immune systems—during hospital visits. Researchers will see if offering, prescribing, and giving vaccines in the hospital increases how many people get vaccinated. The …

This study follows 250 adults in Finland who were previously screened for celiac disease to see how early diagnosis affects their long-term health, diet habits, and quality of life. Researchers will track symptoms, gluten-free diet adherence, and overall well-being. The goal is t…

This study looks at eating behaviors in teenagers aged 11-17 with celiac disease compared to healthy teens. Participants fill out questionnaires about their eating habits and concerns. A smaller group newly diagnosed with celiac disease will be followed for two years to see how t…

This study tests a digital diary called MyMedDiary in 120 children (ages 2-18) newly diagnosed with celiac disease. The app helps families track gluten-free foods and spot hidden sources of gluten. Researchers want to see if the app improves diet adherence compared to traditional…

This study looks at 140 children with celiac disease, ages 2 to 18, who have been on a gluten-free diet for at least 6 months. Researchers will compare a questionnaire and rapid urine/stool tests to standard blood tests to see which methods best measure diet adherence. The goal i…