Brain edema
MONDO:0006684Increased intracellular or extracellular fluid in brain tissue. Cytotoxic brain edema (swelling due to increased intracellular fluid) is indicative of a disturbance in cell metabolism, and is commonly associated with hypoxic or ischemic injuries (see hypoxia, brain). An increase in extracellular fluid may be caused by increased brain capillary permeability (vasogenic edema), an osmotic gradient, local blockages in interstitial fluid pathways, or by obstruction of csf flow (e.g., obstructive hydrocephalus). (From Childs Nerv Syst 1992 Sep; 8(6):301-6)
23 clinical trials for this condition and its sub-types, 23 tagged with Brain edema itself.
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Balloon 'Postconditioning' may shield brain after stroke
Disease control CompletedThis study tested a procedure called rapid local ischemic postconditioning in 25 people who had a stroke and successful clot removal. Right after reopening the blocked artery, doctors briefly inflated and deflated a balloon in the neck to temporarily stop blood flow, aiming to he…
Sponsor: Shanghai Jiao Tong University Affiliated Sixth People's Hospital • Aim: Disease control
Last updated Jun 27, 2026 08:00 UTC
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Brain pressure monitor could boost recovery after major bleed
Disease control CompletedThis study looked at whether using a device to measure pressure inside the skull helps doctors treat people with a large brain bleed. 193 patients were randomly assigned to get either standard care or care guided by the pressure monitor. The goal was to see if the monitor helped …
Sponsor: Xiangya Hospital of Central South University • Aim: Disease control
Last updated Jun 26, 2026 15:06 UTC
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Could a heart drug help stroke patients?
Disease control CompletedThis study tested whether trimetazidine, a drug usually used for heart conditions, can improve outcomes in people who had an acute ischemic stroke. 60 adults were enrolled within 6-12 hours of their stroke. Researchers measured inflammation levels, stroke severity, and disability…
Phase 3 • Sponsor: Ain Shams University • Aim: Disease control
Last updated Jun 26, 2026 14:45 UTC
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Blood and brain scans may predict stroke deterioration
Knowledge-focused CompletedThis completed study looked at 213 people with acute ischemic stroke to see if combining brain scans with blood tests could better predict complications like brain swelling or bleeding. Researchers also used a mouse model to study how brain cells change after stroke. The goal is …
Sponsor: University of Florence • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:07 UTC
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AI boosts brain scan reading speed and accuracy?
Knowledge-focused CompletedThis study tested whether an artificial intelligence (AI) tool called qER 2.0 EU helps doctors and other health professionals read head CT scans more accurately and quickly. Thirty-three readers, including radiologists, emergency doctors, and radiographers, reviewed 150 scans wit…
Sponsor: Oxford University Hospitals NHS Trust • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:00 UTC