Altitude sickness

This study follows 20,000 healthy Chinese adults aged 40-75 living at various altitudes to see if chronic low oxygen levels increase the risk of multiple system atrophy (MSA), a rare and fatal brain disease. Participants undergo checkups and overnight oxygen monitoring, then are …

This study tests whether acetazolamide, a drug already used for altitude sickness, can reduce inflammation and immune system activation caused by high altitude. Nineteen healthy adults will take either the drug or a placebo before and during a stay at 3800 meters. Researchers wil…

This study looks at whether human milk oligosaccharides (HMOs), a key ingredient in breast milk, can help adults living in Antarctica for a year maintain a healthy gut, immune system, and metabolism. Twenty-six healthy adults will take either an HMO supplement or a placebo. Resea…

This study follows 30 lung transplant recipients and healthy volunteers as they prepare for and climb Mount Aconcagua (6,971 meters). Participants first use a special tent at home for eight weeks to get used to lower oxygen levels. Then, a team monitors their lung function, oxyge…

This study tests whether a drug can help red blood cells work better in low-oxygen (hypoxia) and cold (hypothermia) conditions, which are common in high-altitude or military environments. Researchers will measure how the drug affects red blood cell energy and antioxidant defenses…