Altitude sickness

This study tested whether the drug acetazolamide (commonly used for altitude sickness) reduces pressure in the lung arteries differently in women compared to men when traveling to 3,600 meters. Over 300 healthy, non-smoking adults took either the drug or a placebo starting 24 hou…

This study looked at whether the drug acetazolamide (Diamox) prevents acute mountain sickness (AMS) equally well in women and men. Over 300 healthy adults traveled to high altitude and took either the drug or a placebo. The goal was to see if women, who may have higher drug level…

This study looked at whether training at high altitudes causes or worsens exercise-induced bronchoconstriction (EIB) in 64 elite race walkers. Participants completed lung function tests, treadmill challenges, and blood draws at both low and high altitudes over 2-4 months. The goa…

This study looked at whether giving extra oxygen to people who live high in the mountains and have high altitude pulmonary hypertension (a type of high blood pressure in the lungs) helps them walk farther. Twenty-four participants completed the trial. Researchers measured how far…

This study looks at whether taking hot spring baths can help young athletes recover their thinking skills and physical performance while training at simulated high altitudes. Twenty-seven healthy teens who already train regularly will be randomly assigned to hot spring baths, pla…

This trial investigates whether a short stay at high altitude (up to 3,545 meters) is safe for people with asymptomatic moderate or severe aortic stenosis. Participants will undergo heart tests—including ECG, echocardiography, and exercise stress tests—both at low altitude and af…

This study tested whether taking hot spring baths (38°C for 20 minutes, three times a week) helps healthy teen athletes adapt to training at 1600 meters altitude. 27 participants were split into three groups: hot spring baths, hot water baths, or standard recovery. Researchers me…

This study looked at whether the phase of a woman's menstrual cycle affects her chances of getting acute mountain sickness (AMS) when traveling to high altitude. Researchers followed 91 healthy women as they spent two days at 3600 meters (about 11,800 feet). The goal was to see i…

This study looked at how low oxygen (like at high altitudes) affects pilots' bodies and their ability to fly. 17 healthy volunteers did flight simulator tasks while breathing air that mimicked 8,000 or 12,000 feet. Researchers measured heart rate, blood pressure, oxygen levels, a…

This study looked at how being at high altitude (over 3,400 meters) affects the performance of highly trained medical rescuers. Twenty doctors performed simulated patient care scenarios at altitude, with and without extra oxygen, and after spending a night there. The goal was to …

This study looked at whether pioglitazone, a drug used for diabetes, can help the body use sugar from food during exercise at high altitude. Nine healthy men took either the drug or a placebo for five days, then exercised on a treadmill in a chamber simulating high altitude. Rese…

This study looked at how being at a real high altitude (3,000 meters in a mountain hut) compares to a machine that mimics low-oxygen conditions. Twenty healthy adults took part, and researchers measured things like brain oxygen, blood oxygen, heart rate, sleep quality, and altitu…

This study looked at 24 people with high-altitude pulmonary hypertension who live above 2500 meters. Researchers measured their sleep breathing at 3200 meters and again after moving to 760 meters. The goal was to see if lower altitude improves oxygen levels and reduces breathing …

This study looked at 24 people with high altitude pulmonary hypertension who live above 8,200 feet. Researchers measured how far they could walk in 6 minutes at their home altitude (10,500 feet) and after moving to a lower altitude (2,500 feet). The goal was to see if relocating …

This study looked at 24 people with high altitude pulmonary hypertension (HAPH) who live above 2,500 meters. Researchers measured their lung blood pressure at 3,200 meters and then after moving to 760 meters for one night and seven nights. The goal was to see if simply being at a…

This study looked at whether giving extra oxygen can lower blood pressure in the lungs of people who live above 2500 meters and have high altitude pulmonary hypertension. Researchers measured heart changes with ultrasound in 48 highlanders while they breathed either oxygen or reg…