Acute asthma

This Phase 2 trial tests whether adding rademikibart (a shot) to standard care can help adults and teens with asthma and type 2 inflammation avoid hospital visits or needing more steroids during an attack. About 160 participants will receive either the drug or a placebo. The main…

This study tests whether a high dose of montelukast (Singulair), given by mouth, can help children aged 4 to 12 who are in the hospital with a moderate or severe asthma attack. The goal is to find the best dose for a future larger study. Children receive either the high-dose mont…

This study tested a dietary supplement containing immune-supporting nutrients and postbiotics in 40 children aged 5–12 with asthma and/or allergic rhinitis. The goal was to see if the supplement could improve symptom control over 6 months. Researchers also looked at changes in im…

This study looked at whether giving hospital-level care to acutely ill adults in their own homes in rural areas works well. 160 people with various conditions like infections, heart failure, or COPD took part. The goal was to see if this approach could lower costs and help patien…

This pilot study tested whether giving two asthma medications (ipratropium and dexamethasone) to children during ambulance transport can reduce hospital admissions. The study included 44 children aged 2 to 17 with severe wheezing. The goal was to see if this early treatment is fe…

This study compared a single IV dose of dexamethasone to three days of oral prednisolone for treating acute asthma attacks in children aged 2 to 12. A total of 224 children participated, and the severity of their asthma was measured using a standard score. The goal was to see if …

This international survey asks practicing physicians how they diagnose and treat acute asthma exacerbations—sudden worsening of asthma symptoms. It aims to uncover variations in clinical practice, including medication choices and use of breathing support. The findings could revea…

This study tests a soft, wearable stethoscope that can continuously listen to a child's breathing and detect wheezing, a sign of an asthma attack. Researchers at Emory University will enroll 25 children hospitalized for asthma to wear the device for up to 8 hours. The goal is to …