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One shot vs three days: which steroid wins for Kids' asthma?

NCT ID NCT07275593

Symptom relief Sponsor: Muhammad Aamir Latif Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study compared a single IV dose of dexamethasone to three days of oral prednisolone for treating acute asthma attacks in children aged 2 to 12. A total of 224 children participated, and the severity of their asthma was measured using a standard score. The goal was to see if the one-dose option works as well as the longer treatment.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Dexamethasone (single IV dose) and prednisolone (oral for 3 days)
What this could lead to
If dexamethasone works as well as prednisolone, it could simplify treatment by requiring only one dose instead of three days of medication.
What could go wrong
This is a small, completed study with 224 children, so results may not apply to all cases. Also, the study excluded children with severe attacks or other chronic conditions.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

224 people

The number who actually took part.

Started

Nov 2024

Finished

Apr 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

2 to 12 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Children of any gender * Aged 2-12 years * Presenting with acute exacerbation of asthma within 24-hours Exclusion Criteria: * Children with PRAM score of ≥ 10 * Used oral or parenteral corticosteroids in last 4-weeks * With any chronic condition of lungs (TB, cystic fibrosis), liver (chronic liver disease), kidneys (chronic kidney disease, nephrotic syndrome) or blood (thalassemia, malignancy)

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Conditions

The condition(s) this trial relates to.

acute asthma status asthmaticus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Acute exacerbation of asthma

Contacts and locations

Locations

  • Nishtar Medical University Hospital

    Multan, Punjab Province, 66000, Pakistan

More trials for these conditions

Other studies related to the condition(s) this trial covers.