Can a monthly shot keep arteries clear after a heart attack?

NCT ID NCT07276282

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether ziltivekimab, a monthly injection that reduces inflammation, can improve artery health in people who have recently had a heart attack. About 332 participants will receive either the drug or a placebo, alongside standard care. Researchers will use special imaging to measure changes in artery plaque over 15 months.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

ziltivekimab

What this could lead to

If it works, this could point toward a new treatment to reduce artery plaque and prevent future heart attacks in people who have already had one.

What could go wrong

This is a phase 3 trial, but it is still early to know if ziltivekimab will meaningfully reduce heart attacks. The main outcomes are imaging changes, not clinical events, and the drug may not work or could have side effects.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

acute myocardial infarction atherosclerosis coronary artery disorder coronary atherosclerosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Bern University Hospital, Inselspital Bern

    RECRUITING

    Bern, Switzerland

    Contact