Can a monthly shot keep arteries clear after a heart attack?
NCT ID NCT07276282
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether ziltivekimab, a monthly injection that reduces inflammation, can improve artery health in people who have recently had a heart attack. About 332 participants will receive either the drug or a placebo, alongside standard care. Researchers will use special imaging to measure changes in artery plaque over 15 months.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- ziltivekimab
- What this could lead to
- If it works, this could point toward a new treatment to reduce artery plaque and prevent future heart attacks in people who have already had one.
- What could go wrong
- This is a phase 3 trial, but it is still early to know if ziltivekimab will meaningfully reduce heart attacks. The main outcomes are imaging changes, not clinical events, and the drug may not work or could have side effects.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Bern University Hospital, Inselspital Bern
RECRUITINGBern, Switzerland
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