Can a new pill bring back skin color in vitiligo?

NCT ID NCT07108283

Recruiting now Disease control Sponsor: Takeda Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Aug 14, 2026 · Updated 2 times

Summary

This study tests a drug called zasocitinib in adults with nonsegmental vitiligo, an autoimmune condition that causes white patches on the skin. About 200 participants will take either the drug or a placebo for up to a year. The main goal is to see if the drug can improve skin color on the face by at least 75% after 6 months.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: zasocitinib (also known as TAK-279)
What this could lead to: If it works, this could lead to a new treatment option that helps restore skin color in people with vitiligo.
What could go wrong: This is an early Phase 2 trial with only 200 participants, so results may not apply to everyone. The drug may not work better than placebo, and side effects are still being studied.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

generalized vitiligo vitiligo

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

NONSEGMENTAL VITILIGO

Contacts and locations

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Study contacts

Contact

Email: •••••@•••••

Locations

ACRC Trials
RECRUITING

Plano, Texas, 75024, United States
Advanced Clinical Research Institute (ACRI)
RECRUITING

Tampa, Florida, 33607, United States
Arke SMO SA de CV
NOT_YET_RECRUITING

Veracruz, 91900, Mexico
Assistance Publique-Hopitaux de Paris (AP-HP) - Hopitaux Universitaires Henri Mondor (Hopital Henri-Mondor)
RECRUITING

Créteil, 94010, France
Azienda Usl Toscana Centro
RECRUITING

Florence, 50125, Italy
Bexley Dermatology (legal entity - Dermatologists of Southwestern Ohio, LLC)
WITHDRAWN

Bexley, Ohio, 43209, United States
Bordeaux University Hospital
RECRUITING

Bordeaux, 33000, France
Brunswick Dermatology Center (BDC)
RECRUITING

Fredericton, New Brunswick, E3B 1G9, Canada
CRI Centro Regiomontano de Investigation SC
NOT_YET_RECRUITING

Monterrey, New Leon, 64060, Mexico
Cabinet Medical du Dr Ruer
RECRUITING

Martigues, 13500, France
Center for Dermatology Clinical Research, Inc.
RECRUITING

Fremont, California, 94538, United States
Centre Hospitalier Le Mans (CHM)
RECRUITING

Le Mans, 72000, France
Centre Hospitalier Universitaire (CHU) de Toulouse - Hopital Larrey
RECRUITING

Toulouse, 31059, France
Centre Hospitalier Universitaire de Nice - Hopital l'Archet
NOT_YET_RECRUITING

Nice, 6202, France
Centre de Recherche Dermatologique de Quebec
RECRUITING

Québec, Quebec, G1V 4X7, Canada
Centro de Dermatologia de Monterrey
NOT_YET_RECRUITING

Monterrey, Nuevo León, 64460, Mexico
Clinica Universidad de Navarra
RECRUITING

Madrid, 28027, Spain
Clinica de Enfermedades Cronicas y de Procedimientos Especiales
NOT_YET_RECRUITING

Morelia, Predeterminado, 58249, Mexico
DelRicht Research (Audubon Dermatology)
RECRUITING

New Orleans, Louisiana, 70115, United States
DelRicht Research - Dermatology
RECRUITING

Baton Rouge, Louisiana, 70809, United States
Dermatology Trial Associates
RECRUITING

Bryant, Arkansas, 72022, United States
Dermedic Jacek Zdybski
RECRUITING

Kielce, Świętokrzyskie Voivodeship, 25-553, Poland
Dermodent Centrum Medyczne Aldona Czajkowska Rafal Czajkowski
RECRUITING

Osielsko, Kuyavian-Pomeranian Voivodeship, 86-031, Poland
Dermoklinika Centrum Medyczne
RECRUITING

Lodz, Łódź Voivodeship, 90-436, Poland
ETG Warszawa
RECRUITING

Warsaw, 02-677, Poland
Encore Medical Research of Boynton Beach LLC.
RECRUITING

Boynton Beach, Florida, 33436, United States
Encore Medical Research of Weston LLC
RECRUITING

Weston, Florida, 03331, United States
First Affiliated Hospital of Xi 'an Jiaotong University
RECRUITING

Xi'an, Shaanxi, 100176, China
First OC Dermatology
RECRUITING

Fountain Valley, California, 92708, United States
Fondazione Policlinico A. Gemelli
RECRUITING

Rome, 00168, Italy
Gyncentrum Sp. z o.o.
RECRUITING

Katowice, 40-600, Poland
Hamzavi Dermatology - Canton
RECRUITING

Canton, Michigan, 48187, United States
Hangzhou Third People's Hospital
RECRUITING

Hangzhou, Zhejiang, 310009, China
Hospital Universitario La Paz (HULP)
RECRUITING

Madrid, 28034, Spain
Hospital Universitario Ramon y Cajal
RECRUITING

Madrid, 28034, Spain
Hospital Universitario Reina Sofia
RECRUITING

Córdoba, 14004, Spain
Hospital Universitario de Gran Canaria Doctor Negrin
RECRUITING

Las Palmas de Gran Canaria, Las Palmas, 35010, Spain
Hospital de Manises
RECRUITING

Valencia, 46005, Spain
Huashan Hospital of Fudan University
RECRUITING

Shanghai, Shanghai Municipality, 200040, China
Humanitas Research Hospital
RECRUITING

Rozzano, Milan, 20089, Italy
Istituto Dermopatico Immacolata IDI, IRCCS
RECRUITING

Rome, Roma, 00167, Italy
Klinika Dermatologii i Dermatologii Onkologicznej Uniw. Szp. Klin. in Rzeszow
RECRUITING

Rzeszów, 35-055, Poland
Kume Clinic - Sakai
RECRUITING

Nishi-ku, Osaka, 593-8324, Japan
LEADER research
RECRUITING

Hamilton, Ontario, L8L 3C3, Canada
Lawrence J Green LLC
RECRUITING

Rockville, Maryland, 20850, United States
Markowitz Medical dba Optiskin
RECRUITING

New York, New York, 10128, United States
Medical University of South Carolina
RECRUITING

Charleston, South Carolina, 29425, United States
Mount Sinai
WITHDRAWN

New York, New York, 10028, United States
Nagoya City University Hospital
RECRUITING

Nagoya, Aichi-ken, 467-8602, Japan
Nippon Medical School Hospital
RECRUITING

Bunkyo-ku, Tokyo, 113-8603, Japan
North York Research Inc
RECRUITING

Toronto, Ontario, M2N 3A6, Canada
Progressive Clinical Research-San Antonio
RECRUITING

San Antonio, Texas, 78213, United States
SKiN Centre for Dermatology
RECRUITING

Peterborough, Ontario, K9J 5K2, Canada
San Marcus Research Clinic, Inc.
RECRUITING

Miami Lakes, Florida, 33014, United States
SimcoDerm Medical and Surgical Dermatology Centre
RECRUITING

Barrie, Ontario, L4M 7G1, Canada
Skinsense Medical Research
RECRUITING

Saskatoon, Saskatchewan, S7K 2C1, Canada
Spedali Civili Hospital
NOT_YET_RECRUITING

Brescia, 25123, Italy
Texas Dermatology and Laser Specialists
RECRUITING

San Antonio, Texas, 78218, United States
The Centre for Clinical Trials
RECRUITING

Oakville, Ontario, L6J 7W5, Canada
The First Affiliated Hospital of Kunming Medical College
RECRUITING

Kunming, Yunnan, 650032, China
The First Hospital of Wuhan
RECRUITING

Wuhan, Hubei, 430022, China
The Vitiligo & Pigmentation Institute of Southern California
RECRUITING

Los Angeles, California, 90036, United States
Therapeutics Clinical Research
RECRUITING

San Diego, California, 92123, United States
Toho University-Sakura Hospital Medical Center
RECRUITING

Sakura-shi, Chiba, 285-8741, Japan
Tokyo Medical University Hospital
RECRUITING

Tokyo, TAkyA, 160-0023, Japan
Twoja Przychodnia Szczecinskie Centrum Medyczne Sp. z o.o.
RECRUITING

Szczecin, West Pomeranian Voivodeship, 71-212, Poland
UC Davis Department of Dermatology
RECRUITING

Sacramento, California, 95816, United States
UT Health Science Center Houston
RECRUITING

Bellaire, Texas, 77401, United States
Weill Cornell Medicine
RECRUITING

New York, New York, 10075, United States
dermMedica Sp. z o.o.
RECRUITING

Wroclaw, Lower Silesian Voivodeship, 51-503, Poland

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