New cream could help kids with vitiligo regain skin color

NCT ID NCT06804811

Recruiting now Disease control Sponsor: Incyte Corporation Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jul 23, 2026 · Updated 5 times

Summary

This study tests a cream called ruxolitinib in children aged 6 to 12 with nonsegmental vitiligo, a condition that causes white patches on the skin. The cream is applied twice daily to affected areas. The goal is to see if it can safely restore skin color. About 250 children will participate.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: ruxolitinib cream
What this could lead to: If successful, this could offer a topical treatment to restore skin color in children with vitiligo, reducing visible patches.
What could go wrong: This is a phase 3 trial, but results may not work for all children, and long-term safety is still being studied. Side effects like skin irritation are possible.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

generalized vitiligo vitiligo

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

NONSEGMENTAL VITILIGO

Contacts and locations

Show contact details

Study contacts

Contact

Email: •••••@•••••
Contact

Email: •••••@•••••

Locations

28 Diagnostic and Consultative Center
RECRUITING

Sofia, 01528, Bulgaria
A.O. Policlinico Sant'Orsola Malpighi-Universita Degli Studi Di Bologna
RECRUITING

Bologna, 40138, Italy
Amsterdam Umc Research Bv
RECRUITING

Amsterdam, 1105 AZ, Netherlands
Azienda Ospedale Universita Di Padova
RECRUITING

Padua, 35100, Italy
Azienda Ospedaliera Spedali Civili Di Brescia-Universita Degli Studi Di Brescia
RECRUITING

Brescia, 25123, Italy
Azienda Ospedaliero Universitaria Federico Ii Di Napoli
RECRUITING

Naples, 80131, Italy
Azienda Ospedaliero-Universitaria Policlinico Vittorio Emanuele Ospedale Gaspare Rodolico Di Catania
RECRUITING

Catania, 95123, Italy
Care Clinic Sp. Z O.O.
RECRUITING

Katowice, 40-568, Poland
Centre Hospitalier Intercommunal de Creteil
RECRUITING

Créteil, 75571, France
Centre Hospitalier Universitaire (Chu) de Bordeaux - Groupe Hospitalier Pellegrin
RECRUITING

Bordeaux, 33076, France
Centre Hospitalier Universitaire (Chu) de Toulouse - Hopital Larrey
RECRUITING

Toulouse, 31059, France
Centre Hospitalier Universitaire de Nantes (Chu de Nantes) - Hopital Hotel Dieu
RECRUITING

Nantes, 44093, France
Centre Hospitalier Universitaire de Nice,Hopital L Archet
RECRUITING

Nice, 06200, France
Centre Hospitalier Victor Dupouy
RECRUITING

Argenteuil, 95107, France
Centro Hospitalar E Universitario Coimbra
RECRUITING

Coimbra, 3000-075, Portugal
Centro Hospitalar de Lisboa Central - Hospital Santo Antonio Dos Capuchos
RECRUITING

Lisbon, 1169-050, Portugal
Centro de Investigaciones Medicas Mar Del Plata
RECRUITING

Mar del Plata, B7600FYK, Argentina
Centrum Badan Klinicznych Pi-House Sp. Z O.O.
RECRUITING

Gdansk, 80-546, Poland
Charite - Universitaetsmedizin Berlin - Campus Charite Mitte (Ccm)
RECRUITING

Berlin, 10117, Germany
Chu Nancy
RECRUITING

Vandœuvre-lès-Nancy, 54500, France
Clinexpert
RECRUITING

Budapest, 01033, Hungary
Consultorios Medicos Dr. Doreski
RECRUITING

Buenos Aires, C1426ABP, Argentina
Croydon University Hospital
NOT_YET_RECRUITING

Croydon, CR7 7YE, United Kingdom
Debreceni Egyetem Klinikai Kozpon Belgyogy Klinika
RECRUITING

Debrecen, 04032, Hungary
Derma Internacional S.A.
RECRUITING

Buenos Aires, C1426, Argentina
Dermedic Iwona Zdybska
RECRUITING

Lublin, 20-607, Poland
Dermodent Centrum Medyczne Aldona Czajkowska Rafał Czajkowski
RECRUITING

Osielsko, 86-031, Poland
Diagnostic Consultation Center Xx - Sofia Eood
RECRUITING

Sofia, 01618, Bulgaria
Diamond Clinic Specjalistyczne Poradnie Lekarskie
RECRUITING

Krakow, 31-559, Poland
Evimed Sp. Z O. O.
RECRUITING

Warsaw, 02-625, Poland
Fondazione Policlinico Universitario Agostino Gemelli Irccs
RECRUITING

Rome, 00137, Italy
Great Ormond Street Hospital For Children Nhs Foundation Trust
NOT_YET_RECRUITING

London, WC1N 3JH, United Kingdom
Guys Hospital
NOT_YET_RECRUITING

London, SE1 9RT, United Kingdom
Hautklinik Universitatsklinikum Erlangen
RECRUITING

Erlangen, 91054, Germany
Herlev and Gentofte Hospital
RECRUITING

Hellerup, 02900, Denmark
Hopital Universitaire Necker Enfants Malades
RECRUITING

Paris, 75015, France
Hopital Universitaire de Bruxelles (Academisch Ziekenhuis Brussel)
RECRUITING

Brussels, 01070, Belgium
Hospices Civils de Lyon (Hcl) - Hopital Edouard Herriot (Heh)
RECRUITING

Lyon, 69003, France
Hospital Del Nino Jesus
RECRUITING

San Miguel de Tucumán, 04000, Argentina
Hospital Geral de Santo Antonio
RECRUITING

Porto, 4099-001, Portugal
Hospital Infantil Unversitario Nino Jesus
RECRUITING

Madrid, 28009, Spain
Hospital Italiano de Buenos Aires
RECRUITING

Buenos Aires, C1181ACH, Argentina
Hospital Sant Joan de Deu Barcelona
RECRUITING

Esplugues de Llobregat, 08950, Spain
Hospital Universitari Germans Trias I Pujol
RECRUITING

Badalona, 08916, Spain
Hospital Universitario Austral
RECRUITING

Derqui-pilar, B16290DT, Argentina
Hospital Universitario Fundacion Alcorcon
RECRUITING

Alcorcón, 28922, Spain
Hospital Universitario Miguel Servet de Zaragoza
RECRUITING

Zaragoza, 50009, Spain
Hospital de La Santa Creu I Sant Pau
RECRUITING

Barcelona, 08026, Spain
Instituto de Neumonologia Y Dermatologia
RECRUITING

Buenos Aires, C1425BEA, Argentina
Irccs Ospedale Pediatrico Bambino Gesu
NOT_YET_RECRUITING

Rome, 00165, Italy
Istituto Di Ricovero E Cura A Carattere Scientifico (Ircss)
RECRUITING

Roma, 00167, Italy
Katholisches Kinderkrankenhaus Wilhelmstift
RECRUITING

Hamburg, 22149, Germany
Klinikum Rechts Der Isar Der Technischen Universitaet Muenchen (Hopital Rechts Der Isar)
RECRUITING

München, 81675, Germany
Manor Hospital (Walsall) - Walsall Healthcare Nhs Trust
NOT_YET_RECRUITING

Walsall, WS2 9PS, United Kingdom
Mc Euroderma Clinic
RECRUITING

Sofia, 01606, Bulgaria
Medical Center Asklepii Ood
RECRUITING

Dupnitsa, 02600, Bulgaria
Medical Center Unimed Eood
RECRUITING

Sevlievo, 05400, Bulgaria
Medical University Innsbruck
RECRUITING

Innsbruck, 06020, Austria
Mhat Dr. Tota Venkova Ad
RECRUITING

Gabrovo, 05300, Bulgaria
Polyclinique de Courlancy
NOT_YET_RECRUITING

Reims, 51100, France
Psoriahue
RECRUITING

Buenos Aires, 01425, Argentina
Sanos Clinic
RECRUITING

Herlev, 02730, Denmark
Sheffield Childrens Hospital
RECRUITING

Sheffield, S10 2TH, United Kingdom
The Royal London Hospital - Barts Health Nhs Trust
RECRUITING

London, E1 1FR, United Kingdom
Twoja Przychodnia - Medyczne Nowa Sol
RECRUITING

Nowa Sól, 67-100, Poland
Twoja Przychodnia Scm
RECRUITING

Szczecin, 71-500, Poland
Umhat Aleksandrovska
RECRUITING

Sofia, 01431, Bulgaria
Universitaetsklinikum Graz
RECRUITING

Graz, 08036, Austria
Universitaetsklinikum Leipzig
RECRUITING

Leipzig, 04103, Germany
Universitair Ziekenhuis Gent
RECRUITING

Ghent, 09000, Belgium
Universitair Ziekenhuis Leuven
RECRUITING

Leuven, 03000, Belgium
Universitatsmedizin Der Johannes Gutenberg-Universitat Mainz Iii
RECRUITING

Mainz, 55131, Germany
Universite Catholique de Louvain (Ucl) - Cliniques Universitaires Saint-Luc
RECRUITING

Woluwe-Saint-Lambert, 01200, Belgium
University Hospital Muenster
RECRUITING

Münster, 48149, Germany
University Medical Center Schleswig-Holstein
RECRUITING

Kiel, 24105, Germany
University of Pecs-Clinical Center
RECRUITING

Pécs, 07632, Hungary
University of Szeged
RECRUITING

Szeged, 06720, Hungary
Uniwersytecki Szpital Kliniczny Im. Fryderyka Chopina W Rzeszowie
RECRUITING

Rzeszów, 35-055, Poland
Uoc Dermatologia Ospedale Maggiore Policlinico, Fondazione Irccs Ca' Granda
RECRUITING

Milan, 20122, Italy

More trials for these conditions

Other studies related to the condition(s) this trial covers.