New drug combo may let CLL patients pause treatment

NCT ID NCT04458610

First seen Jan 13, 2026 · Last updated Apr 25, 2026 · Updated 9 times

Summary

This study tests a combination of two drugs, zanubrutinib and rituximab, in 60 adults with untreated chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma. The goal is to see if the combo can control the disease and allow patients to stop treatment for at least 6 months. Participants take both drugs by mouth or infusion, and researchers track how long they stay in remission without needing more therapy.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for CHRONIC LYMPHOCYTIC LEUKEMIA/SMALL LYMPHOCYTIC LYMPHOMA are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Locations

  • M D Anderson Cancer Center

    Houston, Texas, 77030, United States

Conditions

Explore the condition pages connected to this study.