New drug combo aims for long remission in untreated CLL patients

NCT ID NCT04458610

First seen Jan 13, 2026 · Last updated Jun 08, 2026 · Updated 17 times

Summary

This study is for adults with chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL) who have not yet had treatment. It tests a combination of two drugs: zanubrutinib (which blocks a protein that helps cancer cells grow) and rituximab (an antibody that helps the immune system attack cancer cells). The main goal is to see how many patients can stop treatment and stay in remission for at least 6 months. About 60 people will take part.

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Contacts and locations

Locations

  • M D Anderson Cancer Center

    Houston, Texas, 77030, United States

Conditions

Explore the condition pages connected to this study.