New drug XmAb20717 tested in rare cancers – trial suspended

NCT ID NCT05337735

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This phase II trial tests the safety and effectiveness of a drug called XmAb20717 in 140 people with advanced rare cancers, including mesothelioma, lymphoma, and small cell lung cancer. The drug is given by IV. The main goal is to see if tumors shrink. The trial is currently suspended, so results are pending.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

XmAb20717 (a drug given by IV)

What this could lead to

If it works, this could offer a new treatment option for people with advanced rare cancers that are hard to treat.

What could go wrong

This trial is early (phase II) and currently suspended, so results are uncertain. The drug may not shrink tumors or could cause side effects.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

cervical carcinoma Hodgkins lymphoma Lynch syndrome Mesothelioma, Malignant neuroendocrine carcinoma peritoneal mesothelioma pleural mesothelioma small cell lung carcinoma Uterine Cervical Neoplasms

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • M D Anderson Cancer Center

    Houston, Texas, 77030, United States