Can a collagen patch replace a palate graft for Better-Looking dental implants?
NCT ID NCT06837688
First seen Sep 01, 2026 · Last updated Sep 02, 2026 · Updated 1 time
Summary
This trial tests whether a collagen matrix can match the standard tissue graft for improving gum shape around a single dental implant in the front upper jaw. Thirty adults with one missing tooth will receive an implant and then either a graft taken from their palate or a collagen matrix. Researchers will measure changes in gum contour over three months, along with pain, swelling, and patient satisfaction. If the collagen matrix performs similarly, it could reduce the need for a second surgical site and shorten recovery.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Xenogeneic collagen matrix (Mucoderm) compared with connective tissue graft from the patient's palate
- What this could lead to
- If the collagen matrix works as well as the tissue graft, it could offer a less invasive option for improving gum appearance around dental implants, with less pain and faster recovery.
- What could go wrong
- This is a small, early-stage trial with only 30 patients, so results may not apply broadly. The collagen matrix might not match the graft's outcome, and any surgery carries risks like infection or graft failure.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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30 people
The number who actually took part.
- Started
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Mar 2025
- Expected to finish
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Dec 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 60 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Aged 18 years or older. * Good oral hygiene, defined as full-mouth plaque score ≤25%. * Having a single missing tooth in the aesthetic zone of the maxilla. * Tooth extraction occurred at least 3 months prior to enrolment. * Having adequate bone volume for implant placement (bucco-palatal bone dimension of at least 6 mm). * Having at least 5 mm of keratinized tissue width at the implant site. Exclusion Criteria: * Systemic diseases. * Smoking. * Periodontal disease. * Untreated caries lesions. * Need for horizontal bone augmentation at the time of implant placement.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Damascus University
Damascus, 00000, Syria
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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