Small study to compare bone healing in smokers and Non-Smokers after tooth removal

NCT ID NCT07372183

Not yet recruiting Knowledge-focused Sponsor: Marquette University Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This pilot study will look at how well bone heals after a tooth is removed and a bone graft is placed, comparing smokers and non-smokers. Twelve adults will be enrolled to measure bone width and height, and analyze gene activity and tissue samples. The goal is to gather initial data to plan a larger study on smoking's impact on healing.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this study could help design a larger trial that may reveal how smoking affects bone healing after tooth extraction.
What could go wrong: This is a very small pilot study with only 12 participants, so results may not apply broadly. It is observational and not testing a treatment.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Cigarette Smoking injury

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ALVEOLAR BONE GRAFTING BONE HEALING SMOKING ( CIGARETTE) TOOTH EXTRACTION SITE HEALING WOUND HEALING

Contacts and locations

Locations

Marquette University School of Dentistry Graduate Periodontics Clinic

Milwaukee, Wisconsin, 53233, United States

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