Can wound bacteria predict infection after severe leg fractures?
NCT ID NCT01496014
First seen May 10, 2026 · Last updated Jun 19, 2026 · Updated 6 times
Summary
This study examined bacteria in severe leg wounds of 646 adults (ages 18-64) with open tibia fractures or traumatic amputations. Researchers took samples at the time of wound closure to see if certain bacteria led to deep infections within 30 days to one year. The goal was to better understand infection risks and guide antibiotic use.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Allegheny General Hosptial
Pittsburgh, Pennsylvania, 15212, United States
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Barnes Jewish Hospital
St Louis, Missouri, 63110, United States
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Boston Medical Center
Boston, Massachusetts, 02118, United States
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Brown University/Rhode Island Hospital
Providence, Rhode Island, 02905, United States
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Carolinas Medical Center
Charlotte, North Carolina, 28232, United States
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Denver Health and Hospital Authority
Denver, Colorado, 80204, United States
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Duke University Hospital
Durham, North Carolina, 27710, United States
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Emory University Dept of Orthopaedics
Atlanta, Georgia, 30303, United States
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Florida Orthopaedic Institute
Tampa, Florida, 33606, United States
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Grant Medical Center
Columbus, Ohio, 43215, United States
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Harborview Medical Center
Seattle, Washington, 98104, United States
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Hennepin County Medical Center / Minneapolis
Minneapolis, Minnesota, 55415, United States
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Louisiana State University
New Orleans, Louisiana, 70112, United States
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MetroHealth Medical Center
Cleveland, Ohio, 44109, United States
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Naval Medical Center Portsmouth
Portsmouth, Virginia, 23708, United States
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Naval Medical Center San Diego
San Diego, California, 92134, United States
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Ohio State University Medical Center
Columbus, Ohio, 43210, United States
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OrthoIndy at St Vincent
Indianapolis, Indiana, 46260, United States
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Orthopaedic Associates of Michigan, Spectrum Health
Grand Rapids, Michigan, 49503, United States
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Penn State University M.S. Hershey Medical Center
Hershey, Pennsylvania, 17033, United States
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Regions Hospital
Saint Paul, Minnesota, 55101, United States
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San Antonio Miliary Medical Center
Fort Sam Houston, Texas, 78234-6315, United States
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Scott and White Memorial Hospital
Temple, Texas, 76508, United States
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St. Louis Medical Center
St Louis, Missouri, 63110, United States
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Temple University Hospital
Philadelphia, Pennsylvania, 19140, United States
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UCSF Medical Center
San Francisco, California, 94115, United States
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UT Health: The University of Texas Health Science Center at Houston Medical School
Houston, Texas, 77030, United States
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University of Iowa Hospitals & Clinics
Iowa City, Iowa, 52242, United States
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University of Kansas Medical Center
Kansas City, Kansas, 66160, United States
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University of Maryland, R Adams Cowley Shock Trauma Center
Baltimore, Maryland, 21201, United States
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University of Miami Ryder Trauma Center
Miami, Florida, 33101, United States
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University of Mississippi Medical Center
Jackson, Mississippi, 39216, United States
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University of Oklahoma
Oklahoma City, Oklahoma, 73104, United States
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University of Rochester
Rochester, New York, 14642, United States
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University of Utah
Salt Lake City, Utah, 84108, United States
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University of Virginia
Charlottesville, Virginia, 22908, United States
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Vanderbilt University Medical Center
Nashville, Tennessee, 37232, United States
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Wake Forest University Baptist Medical Center
Winston-Salem, North Carolina, 27157-1070, United States
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Walter Reed Military Medical Center
Bethesda, Maryland, 20889, United States
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Walter Reed National Military Medical Center
Bethesda, Maryland, 20889, United States
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.