Whole blood may be just as good as standard transfusions for trauma bleeding

NCT ID NCT04431999

Completed Disease control Sponsor: Direction Centrale du Service de Santé des Armées Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at whether giving whole blood (all blood parts together) works as well as giving separate blood parts (red cells, plasma, platelets) to people with severe bleeding from trauma. About 200 patients who needed a massive transfusion were included. The goal was to see if whole blood corrects bleeding problems just as well, which could simplify emergency care.

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Conditions

The condition(s) this trial relates to.

blood coagulation disease injury vascular hemostatic disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ACUTE HEMORRHAGE COAGULOPATHY TRAUMA

Contacts and locations

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Locations

CHU de Grenoble

Grenoble, 38000, France
CHU de La Cavale Blanche - Brest

Brest, 29200, France
CHU de La Pitié-Salpêtrière

Paris, 75013, France
CHU du Kremlin Bicêtre

Paris, 94270, France
HIA Percy

Clamart, 92140, France
HIA Sainte Anne

Toulon, 83000, France