Lifestyle makeover could slash Alzheimer's risk in genetically vulnerable seniors

NCT ID NCT07646054

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether a year-long virtual lifestyle coaching program—focusing on diet, sleep, and activity—can lower Alzheimer's-related blood markers in 1,200 adults aged 60-80 who carry a genetic risk. Participants wear an Oura ring for tracking and provide blood samples. The goal is to see if lifestyle changes can prevent or delay Alzheimer's disease.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

lifestyle coaching (diet, activity, sleep guidance)

What this could lead to

If successful, this could show that lifestyle changes can help prevent or delay Alzheimer's disease in people with a genetic risk.

What could go wrong

This is an early-stage prevention trial, not a treatment. The intervention is behavioral, so results may vary widely, and it may not show a clear effect on Alzheimer's biomarkers.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Cognitive Dysfunction Alzheimer disease prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Scripps Translational Research Institute

    La Jolla, California, 92037, United States