Lifestyle makeover could slash Alzheimer's risk in genetically vulnerable seniors

NCT ID NCT07646054

Not yet recruiting Prevention Sponsor: Scripps Translational Science Institute Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether a year-long virtual lifestyle coaching program—focusing on diet, sleep, and activity—can lower Alzheimer's-related blood markers in 1,200 adults aged 60-80 who carry a genetic risk. Participants wear an Oura ring for tracking and provide blood samples. The goal is to see if lifestyle changes can prevent or delay Alzheimer's disease.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: lifestyle coaching (diet, activity, sleep guidance)
What this could lead to: If successful, this could show that lifestyle changes can help prevent or delay Alzheimer's disease in people with a genetic risk.
What could go wrong: This is an early-stage prevention trial, not a treatment. The intervention is behavioral, so results may vary widely, and it may not show a clear effect on Alzheimer's biomarkers.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for ALZHEIMER DISEASE (AD) are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

Cognitive Dysfunction Alzheimer disease prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ALZHEIMER DISEASE (AD) MILD COGNITIVE IMPAIRMENT (MCI)

Contacts and locations

Locations

Scripps Translational Research Institute

La Jolla, California, 92037, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.