Vitamin d and k: the Bone-Boosting duo under the microscope

NCT ID NCT04573946

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at how vitamin D and vitamin K interact to affect bone density and fracture risk in older adults. Researchers are analyzing data from over 25,000 participants who took vitamin D and omega-3 supplements or placebos. The goal is to see if people with low vitamin K levels get more bone benefits from vitamin D.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Vitamin D3 (cholecalciferol) and omega-3 fatty acids (fish oil)

What this could lead to

If successful, this could clarify whether vitamin K status influences how well vitamin D supplements protect bones, guiding future bone health recommendations.

What could go wrong

This is an observational analysis of an existing trial, not a new treatment test. Results may show no clear link or may not apply to everyone.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for BONE DENSITY are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

bone fracture

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Brigham and Women's Hospital

    Boston, Massachusetts, 02115, United States