New drug combo aims to ease dystonia symptoms
NCT ID NCT07304089
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This phase 2 trial tests whether VIM0423, a combination of two drugs, can reduce symptoms of isolated dystonia (a movement disorder causing muscle spasms). About 100 adults aged 18-65 with dystonia in at least two body areas will receive either VIM0423 or a placebo. Researchers will measure changes in symptom severity, daily function, and quality of life over the study period.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
VIM0423 (a combination of two drugs: VMA-1001 and VMA-1002)
What this could lead to
If it works, this could point toward a new treatment option to ease dystonia symptoms and improve daily life.
What could go wrong
This is an early phase 2 trial with only 100 people, so results may not apply to everyone. The drug may not work better than placebo, and side effects are still being studied.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Vima Site #002
RECRUITINGFarmington Hills, Michigan, 48334, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Vima Site #004
RECRUITINGScottsdale, Arizona, 85258, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Vima Site #005
NOT_YET_RECRUITINGAtlanta, Georgia, 30329, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Vima Site #006
NOT_YET_RECRUITINGNashville, Tennessee, 37232, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Vima Site #007
RECRUITINGOlney, Maryland, 20832, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Vima Site #008
RECRUITINGMiami, Florida, 33176, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Vima Site #009
RECRUITINGGainesville, Florida, 32608, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Vima Site #011
RECRUITINGRichmond, Virginia, 23233, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Vima Site #012
RECRUITINGHouston, Texas, 77030, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Vima Site #013
NOT_YET_RECRUITINGHouston, Texas, 77030, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Vima Site #014
RECRUITINGAlbuquerque, New Mexico, 87106, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Vima Site #015
RECRUITINGSpokane, Washington, 99202, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Vima Site #016
RECRUITINGMemphis, Tennessee, 38157, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Vima Site #019
RECRUITINGDenver, Colorado, 80113, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Vima Site #020
RECRUITINGPhiladelphia, Pennsylvania, 19107, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Vima Site #021
NOT_YET_RECRUITINGCharleston, South Carolina, 29425, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Vima Site #023
RECRUITINGKirkland, Washington, 98034, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Vima Site #024
NOT_YET_RECRUITINGNew York, New York, 10019, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Vima Site #024
RECRUITINGNew York, New York, 10021, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Vima Site #025
NOT_YET_RECRUITINGDallas, Texas, 75390, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Vima Site #026
RECRUITINGGeorgetown, Texas, 78628, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Vima Site #027
NOT_YET_RECRUITINGChicago, Illinois, 60611, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Vima Site #028
NOT_YET_RECRUITINGSun City, Arizona, 85351, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Vima Site #029
NOT_YET_RECRUITINGPortland, Oregon, 97239, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Vima Site #030
NOT_YET_RECRUITINGLos Angeles, California, 90048, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Vima Site #031
RECRUITINGOrlando, Florida, 32825, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Vima Site #032
NOT_YET_RECRUITINGBoston, Massachusetts, 02215, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Vima Site #033
NOT_YET_RECRUITINGBirmingham, Alabama, 35233, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Vima Site #035
RECRUITINGCincinnati, Ohio, 45212, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Vima Site #036
NOT_YET_RECRUITINGRochester, New York, 14618, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Vima Site #037
NOT_YET_RECRUITINGEast Lansing, Michigan, 48824, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Vima Site #038
RECRUITINGSt Louis, Missouri, 63110, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Vima Site #039
NOT_YET_RECRUITINGScottsdale, Arizona, 85251, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Vima Site #040
RECRUITINGFayetteville, North Carolina, 28304, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Vima Site #041
RECRUITINGOverland Park, Kansas, 66211, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Vima Site #042
RECRUITINGIrvine, California, 92614, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Vima Site #043
RECRUITINGBaltimore, Maryland, 21237, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••