New drug combo aims to ease dystonia symptoms
NCT ID NCT07304089
First seen Jun 27, 2026 · Last updated Aug 05, 2026 · Updated 2 times
Summary
This phase 2 trial tests whether VIM0423, a combination of two drugs, can reduce symptoms of isolated dystonia (a movement disorder causing muscle spasms). About 100 adults aged 18-65 with dystonia in at least two body areas will receive either VIM0423 or a placebo. Researchers will measure changes in symptom severity, daily function, and quality of life over the study period.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- VIM0423 (a combination of two drugs: VMA-1001 and VMA-1002)
- What this could lead to
- If it works, this could point toward a new treatment option to ease dystonia symptoms and improve daily life.
- What could go wrong
- This is an early phase 2 trial with only 100 people, so results may not apply to everyone. The drug may not work better than placebo, and side effects are still being studied.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Email: •••••@•••••
Locations
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Vima Site #002
RECRUITINGFarmington Hills, Michigan, 48334, United States
Contact Email: •••••@•••••
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Vima Site #004
RECRUITINGScottsdale, Arizona, 85258, United States
Contact Email: •••••@•••••
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Vima Site #005
RECRUITINGAtlanta, Georgia, 30329, United States
Contact Email: •••••@•••••
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Vima Site #006
RECRUITINGNashville, Tennessee, 37232, United States
Contact Email: •••••@•••••
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Vima Site #007
RECRUITINGOlney, Maryland, 20832, United States
Contact Email: •••••@•••••
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Vima Site #008
RECRUITINGMiami, Florida, 33176, United States
Contact Email: •••••@•••••
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Vima Site #009
RECRUITINGGainesville, Florida, 32608, United States
Contact Email: •••••@•••••
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Vima Site #011
RECRUITINGRichmond, Virginia, 23233, United States
Contact Email: •••••@•••••
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Vima Site #012
RECRUITINGHouston, Texas, 77030, United States
Contact Email: •••••@•••••
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Vima Site #013
NOT_YET_RECRUITINGHouston, Texas, 77030, United States
Contact Email: •••••@•••••
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Vima Site #014
RECRUITINGAlbuquerque, New Mexico, 87106, United States
Contact Email: •••••@•••••
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Vima Site #015
RECRUITINGSpokane, Washington, 99202, United States
Contact Email: •••••@•••••
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Vima Site #016
RECRUITINGMemphis, Tennessee, 38157, United States
Contact Email: •••••@•••••
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Vima Site #018
RECRUITINGNew York, New York, 10019, United States
Contact Email: •••••@•••••
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Vima Site #019
RECRUITINGDenver, Colorado, 80113, United States
Contact Email: •••••@•••••
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Vima Site #020
RECRUITINGPhiladelphia, Pennsylvania, 19107, United States
Contact Email: •••••@•••••
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Vima Site #021
RECRUITINGCharleston, South Carolina, 29425, United States
Contact Email: •••••@•••••
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Vima Site #023
RECRUITINGKirkland, Washington, 98034, United States
Contact Email: •••••@•••••
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Vima Site #024
RECRUITINGNew York, New York, 10021, United States
Contact Email: •••••@•••••
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Vima Site #025
NOT_YET_RECRUITINGDallas, Texas, 75390, United States
Contact Email: •••••@•••••
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Vima Site #026
RECRUITINGGeorgetown, Texas, 78628, United States
Contact Email: •••••@•••••
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Vima Site #027
RECRUITINGChicago, Illinois, 60611, United States
Contact Email: •••••@•••••
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Vima Site #028
RECRUITINGSun City, Arizona, 85351, United States
Contact Email: •••••@•••••
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Vima Site #029
NOT_YET_RECRUITINGPortland, Oregon, 97239, United States
Contact Email: •••••@•••••
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Vima Site #030
NOT_YET_RECRUITINGLos Angeles, California, 90048, United States
Contact Email: •••••@•••••
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Vima Site #031
RECRUITINGOrlando, Florida, 32825, United States
Contact Email: •••••@•••••
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Vima Site #032
RECRUITINGBoston, Massachusetts, 02215, United States
Contact Email: •••••@•••••
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Vima Site #033
RECRUITINGBirmingham, Alabama, 35233, United States
Contact Email: •••••@•••••
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Vima Site #035
RECRUITINGCincinnati, Ohio, 45212, United States
Contact Email: •••••@•••••
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Vima Site #036
RECRUITINGRochester, New York, 14618, United States
Contact Email: •••••@•••••
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Vima Site #037
RECRUITINGEast Lansing, Michigan, 48824, United States
Contact Email: •••••@•••••
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Vima Site #038
RECRUITINGSt Louis, Missouri, 63110, United States
Contact Email: •••••@•••••
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Vima Site #039
RECRUITINGScottsdale, Arizona, 85251, United States
Contact Email: •••••@•••••
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Vima Site #040
RECRUITINGFayetteville, North Carolina, 28304, United States
Contact Email: •••••@•••••
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Vima Site #041
RECRUITINGOverland Park, Kansas, 66211, United States
Contact Email: •••••@•••••
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Vima Site #042
RECRUITINGIrvine, California, 92614, United States
Contact Email: •••••@•••••
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Vima Site #043
RECRUITINGBaltimore, Maryland, 21237, United States
Contact Email: •••••@•••••
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