A simple ventilation tweak might make Kids' anesthesia safer

NCT ID NCT07767851

First seen Aug 17, 2026 · Last updated Aug 18, 2026 · Updated 1 time

Summary

This trial tests whether using a breathing support method (PEEP and pressure support) during anesthesia induction in children reduces the risk of breathing problems like laryngospasm, bronchospasm, and low oxygen levels. The study will include over 2,000 children aged 3 months to 6 years undergoing surgery with inhalational anesthesia. Half will receive the standard spontaneous breathing approach, while the other half will get the added breathing support. The goal is to see if this technique can lower the rate of respiratory complications during this critical phase.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
A ventilation technique using positive end-expiratory pressure (PEEP) and pressure support ventilation (PSV) during inhalational anesthesia induction in children.
What this could lead to
If effective, this ventilation approach could become a standard practice to reduce serious breathing complications during anesthesia induction in children, improving safety.
What could go wrong
The trial is early and results may not confirm the benefit. The technique requires careful adjustment by an anesthesiologist and may not suit all children.

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Conditions

The condition(s) this trial relates to.

Respiratory Aspiration

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • CHU Toulouse - Hôpitaux des enfants

    Toulouse, 31300, France

  • CHU de Nantes

    Nantes, 44000, France

  • Centre Hospitalier Universitaire de Montpellier

    Montpellier, 34295, France

  • Centre Hospitalier Universitaire de Reims

    Reims, 51092, France

  • Hôpital Armand Trousseau

    Paris, 75012, France

  • Hôpital Femme Mère Enfant

    Lyon, 69677, France

  • Hôpital Robert Debré

    Paris, 75019, France

  • Hôpital de Hautepierre

    Strasbourg, 67200, France

  • Hôpitaux Universitaires de Marseille Timone

    Marseille, 13385, France

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