A simple ventilation tweak might make Kids' anesthesia safer
NCT ID NCT07767851
First seen Aug 17, 2026 · Last updated Aug 18, 2026 · Updated 1 time
Summary
This trial tests whether using a breathing support method (PEEP and pressure support) during anesthesia induction in children reduces the risk of breathing problems like laryngospasm, bronchospasm, and low oxygen levels. The study will include over 2,000 children aged 3 months to 6 years undergoing surgery with inhalational anesthesia. Half will receive the standard spontaneous breathing approach, while the other half will get the added breathing support. The goal is to see if this technique can lower the rate of respiratory complications during this critical phase.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- A ventilation technique using positive end-expiratory pressure (PEEP) and pressure support ventilation (PSV) during inhalational anesthesia induction in children.
- What this could lead to
- If effective, this ventilation approach could become a standard practice to reduce serious breathing complications during anesthesia induction in children, improving safety.
- What could go wrong
- The trial is early and results may not confirm the benefit. The technique requires careful adjustment by an anesthesiologist and may not suit all children.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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CHU Toulouse - Hôpitaux des enfants
Toulouse, 31300, France
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CHU de Nantes
Nantes, 44000, France
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Centre Hospitalier Universitaire de Montpellier
Montpellier, 34295, France
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Centre Hospitalier Universitaire de Reims
Reims, 51092, France
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Hôpital Armand Trousseau
Paris, 75012, France
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Hôpital Femme Mère Enfant
Lyon, 69677, France
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Hôpital Robert Debré
Paris, 75019, France
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Hôpital de Hautepierre
Strasbourg, 67200, France
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Hôpitaux Universitaires de Marseille Timone
Marseille, 13385, France
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