Targeted drug shows promise against rare leukemia

NCT ID NCT01711632

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested a drug called vemurafenib (Zelboraf) in 36 people with hairy cell leukemia that had returned or not responded to standard therapy. The goal was to see how well the drug could clear leukemia from the blood and what side effects it caused. Vemurafenib works by blocking a specific protein (BRAF) that helps the cancer grow.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Dana Farber Cancer Institute

    Boston, Massachusetts, 02115, United States

  • Memorial Sloan Kettering Cancer Center

    New York, New York, 10065, United States

  • Northwestern University

    Evanston, Illinois, 60208, United States

  • Ohio State University

    Columbus, Ohio, 43210, United States

  • Scripps Clinic

    La Jolla, California, 92037, United States

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