New pill aims to shorten COPD Flare-Ups from common cold

NCT ID NCT07610395

First seen Jun 27, 2026 · Last updated Aug 13, 2026 · Updated 2 times

Summary

This study tests an oral drug called vapendavir in 180 adults with COPD who catch a rhinovirus (common cold). The goal is to see if it can reduce the severity and length of breathing symptoms compared to a placebo. Participants are randomly assigned to one of two doses or a placebo, and they report their symptoms daily.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Vapendavir
What this could lead to
If it works, this could point toward a treatment that reduces the severity and duration of cold-related breathing problems in people with COPD.
What could go wrong
This is an early phase 2 trial with only 180 participants, so results may not apply to everyone. The drug may not work better than placebo, and side effects are still being studied.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • 310 Clinical Research, LLC

    RECRUITING

    Inglewood, California, 90301, United States

  • AMR Clinical - Lexington

    RECRUITING

    Lexington, Kentucky, 40509, United States

  • AMR Clinical - Tempe

    RECRUITING

    Tempe, Arizona, 85281, United States

  • Accelerated Clinical Trials, LLC

    RECRUITING

    Snellville, Georgia, 30078, United States

  • Activian Clinical Research

    RECRUITING

    Kingwood, Texas, 77339, United States

  • Apex Clinical Research

    RECRUITING

    San Diego, California, 92120, United States

  • Bioluminux Clinical Research Illinois

    RECRUITING

    Naperville, Illinois, 60540, United States

  • Bioluminux Clinical Research New Jersey

    RECRUITING

    Hamilton, New Jersey, 08690, United States

  • Brooklyn Clinical Research

    RECRUITING

    Brooklyn, New York, 11226, United States

  • CRC Kings Mountain

    RECRUITING

    Kings Mountain, North Carolina, 28086, United States

  • Clinical Research Associates of Central PA, LLC

    RECRUITING

    DuBois, Pennsylvania, 15801, United States

  • Clinical Research of Rock Hill

    RECRUITING

    Rock Hill, South Carolina, 29732, United States

  • Covenant Critical Pulmonary Care

    RECRUITING

    East Point, Georgia, 30344, United States

  • Epic Clinical Research, LLC

    RECRUITING

    Lewisville, Texas, 75057, United States

  • Hometown Urgent Care - Milford

    RECRUITING

    Milford, Ohio, 45150, United States

  • Medquest Translational Sciences

    RECRUITING

    Miami Lakes, Florida, 33016, United States

  • Metropolitan Clinical Research Center

    RECRUITING

    Tamarac, Florida, 33321, United States

  • NewportNativeMD, Inc.

    RECRUITING

    Newport Beach, California, 92663, United States

  • Oakland Medical Research

    RECRUITING

    Troy, Michigan, 48085, United States

  • Patient First Clinical Trials (PFCTRIALS)

    RECRUITING

    Lutherville, Maryland, 21093, United States

  • Preferred Primary Care Physicians - St. Clair

    RECRUITING

    Pittsburgh, Pennsylvania, 15423, United States

  • Remington-Davis, Inc.

    RECRUITING

    Columbus, Ohio, 43215, United States

  • Synergy Health

    RECRUITING

    Bradenton, Florida, 34209, United States

  • Tekton Research

    RECRUITING

    Edmond, Oklahoma, 73013, United States

  • VM Clintrials

    RECRUITING

    Miami Lakes, Florida, 33014, United States

  • Velocity Clinical Research - Anderson

    RECRUITING

    Anderson, South Carolina, 29621, United States

  • Velocity Clinical Research - Binghamton

    RECRUITING

    Binghamton, New York, 13905, United States

  • Velocity Clinical Research - Medford

    RECRUITING

    Medford, Oregon, 97504, United States

  • Velocity Clinical Research - Mobile

    RECRUITING

    Mobile, Alabama, 36608, United States

  • Velocity Clinical Research - Spartanburg

    RECRUITING

    Spartanburg, South Carolina, 29303, United States

  • Velocity Clinical Research - Union

    RECRUITING

    Union, South Carolina, 29379, United States

  • Velocity Clinical Research - Valparaiso

    RECRUITING

    Valparaiso, Indiana, 46383, United States

  • Verexa Health

    RECRUITING

    Dearborn, Michigan, 48126, United States

  • Zenos Clinical Research, LLC

    RECRUITING

    Dallas, Texas, 75230, United States

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