Could a deep breath replace a clamp? new study tests Pain-Free biopsy
NCT ID NCT07496905
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether a simple breathing technique called the Valsalva maneuver can reduce pain during an endometrial biopsy, a procedure that samples the uterine lining. Normally, a clamp (tenaculum) is used to hold the cervix, which can cause pain. The Valsalva maneuver involves taking a deep breath and pushing, which may stabilize the uterus without the clamp. The trial will compare pain levels and procedure success in 120 women undergoing the biopsy.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Valsalva maneuver
What this could lead to
If it works, this simple breathing technique could offer a less painful way to perform endometrial biopsies, reducing the need for instruments that cause discomfort.
What could go wrong
This is a small, early-stage trial with 120 participants, so results may not apply to everyone. The Valsalva maneuver may not reduce pain as effectively as hoped, and some women may still experience discomfort.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Cemil Tascioglu City Hospital
RECRUITINGIstanbul, Turkey (Türkiye)
Contact Phone: •••-•••-•••• Email: •••••@•••••