Could a deep breath replace a clamp? new study tests Pain-Free biopsy

NCT ID NCT07496905

Recruiting now Symptom relief Sponsor: Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether a simple breathing technique called the Valsalva maneuver can reduce pain during an endometrial biopsy, a procedure that samples the uterine lining. Normally, a clamp (tenaculum) is used to hold the cervix, which can cause pain. The Valsalva maneuver involves taking a deep breath and pushing, which may stabilize the uterus without the clamp. The trial will compare pain levels and procedure success in 120 women undergoing the biopsy.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Valsalva maneuver
What this could lead to: If it works, this simple breathing technique could offer a less painful way to perform endometrial biopsies, reducing the need for instruments that cause discomfort.
What could go wrong: This is a small, early-stage trial with 120 participants, so results may not apply to everyone. The Valsalva maneuver may not reduce pain as effectively as hoped, and some women may still experience discomfort.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for ABNORMAL UTERINE BLEEDING are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

Metrorrhagia Pain

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ABNORMAL UTERINE BLEEDING PAIN IN ENDOMETRIAL BIOPSY

Contacts and locations

Locations

Cemil Tascioglu City Hospital
RECRUITING

Istanbul, Turkey (Türkiye)

More trials for these conditions

Other studies related to the condition(s) this trial covers.