ABNORMAL UTERINE BLEEDING

This study is collecting information from 300 women who are scheduled to receive the Cerene cryotherapy device for heavy menstrual bleeding. The goal is to see how well the device works in everyday medical practice, how safe it is, and how it affects quality of life over 12 month…

This study compares a new barbed suture (SYMMCORA) with a standard one (V-Loc) for closing the vaginal cuff after laparoscopic hysterectomy. The goal is to see if the new suture reduces stitching time without increasing complications. About 132 women having elective laparoscopic …

This study tests whether a simple breathing technique called the Valsalva maneuver can reduce pain during an endometrial biopsy, a procedure that samples the uterine lining. Normally, a clamp (tenaculum) is used to hold the cervix, which can cause pain. The Valsalva maneuver invo…

This early-stage trial tests an injectable drug called BT-114143 in 39 women with abnormal uterine bleeding. Participants receive different doses twice daily for three days to see if it safely reduces bleeding. The study also checks for side effects and changes in blood clotting.

This study tests whether adding ketorolac (an anti-inflammatory) to the standard lidocaine numbing shot can reduce pain during office hysteroscopy, a procedure to look inside the uterus. Sixty women with abnormal bleeding will be randomly assigned to get either the combo or lidoc…

This study tests a new surgical approach for women with a uterine niche (a small pocket in the C-section scar) that causes abnormal bleeding. The procedure combines two steps: first, a hysteroscopy to remove unhealthy tissue, then a laparoscopy to cut out and repair the scar. Res…