New amputation technique may restore natural limb movement for amputees

NCT ID NCT06371209

Ongoing Knowledge-focused Sponsor: Brigham and Women's Hospital Source: ClinicalTrials.gov ↗

First seen Jul 09, 2026 · Last updated Jul 10, 2026 · Updated 1 time

Summary

This study looks at a new type of amputation called the Ewing amputation, which connects muscles in the residual limb to allow more natural feedback when using a prosthetic. Researchers will measure muscle activity and movement patterns in people who have had this procedure and compare them to their healthy leg and to standard amputees. The goal is to see if the Ewing amputation helps the brain interpret prosthetic movement more like a real joint.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Modified amputation procedure (Ewing amputation)
What this could lead to: If successful, this could validate a surgical approach that helps amputees feel more natural joint movement and control with their prosthetic limb.
What could go wrong: This is a small observational study, not a treatment trial. It measures movement patterns, not long-term outcomes, and results may not apply to all amputees.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for AGONIST-ANTAGONIST MYONEURAL INTERFACE are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

AGONIST-ANTAGONIST MYONEURAL INTERFACE LOWER EXTREMITY AMPUTATION TRANS-TIBIAL AMPUTATION TRAUMATIC LOWER EXTREMITY AMPUTATION

Contacts and locations

Show contact details

Locations

Mass General Brigham

Boston, Massachusetts, 02129, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.