Neck zap may ease Parkinson's leg stiffness

NCT ID NCT07226284

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether a handheld device that gently stimulates the vagus nerve in the neck can improve leg muscle control, walking, and balance in people with Parkinson's disease. Researchers will compare real stimulation to a sham (fake) version in 75 participants. The goal is to understand if this non-invasive approach can help with movement problems.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

non-invasive vagus nerve stimulator (gammaCore nVNS)

What this could lead to

If it works, this could point toward a drug-free way to improve walking and balance in Parkinson's disease.

What could go wrong

This is an early-stage, small study (75 people) focused on short-term effects. It may not lead to lasting benefits or work for everyone.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Parkinson disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Movement Disorders Laboratory

    RECRUITING

    Minneapolis, Minnesota, 55414, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••