Neck zap may ease Parkinson's leg stiffness

NCT ID NCT07226284

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether a handheld device that gently stimulates the vagus nerve in the neck can improve leg muscle control, walking, and balance in people with Parkinson's disease. Researchers will compare real stimulation to a sham (fake) version in 75 participants. The goal is to understand if this non-invasive approach can help with movement problems.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
non-invasive vagus nerve stimulator (gammaCore nVNS)
What this could lead to
If it works, this could point toward a drug-free way to improve walking and balance in Parkinson's disease.
What could go wrong
This is an early-stage, small study (75 people) focused on short-term effects. It may not lead to lasting benefits or work for everyone.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Movement Disorders Laboratory

    RECRUITING

    Minneapolis, Minnesota, 55414, United States

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