Could gut microbes hold clues to Parkinson's?

NCT ID NCT07749261

First seen Aug 06, 2026 · Last updated Aug 07, 2026 · Updated 1 time

Summary

This exploratory study looks at whether the community of bacteria in the gut and certain related chemical byproducts differ between people with Parkinson's disease and healthy individuals. Researchers will collect one stool sample from 15 people with Parkinson's and 15 matched healthy controls, analyzing the microbes and tryptophan metabolites. The goal is to uncover potential links between gut health and Parkinson's, which could guide larger future studies. No treatment is given, and the findings are for research only.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Stool microbiome and tryptophan metabolite profiling (diagnostic test)
What this could lead to
If differences are found, this could point toward new biomarkers or targets for future Parkinson's research, potentially aiding earlier detection or new treatments.
What could go wrong
This is a small exploratory study with only 30 participants, so findings may not be generalizable. It cannot establish cause and effect or diagnose Parkinson's, and results are for research only.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Laizhou People's Hospital

    Laizhou, Shandong, 261400, China

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